Evidence map›Paper›PMID 26033435›Full record

ArticleObesity surgery2016

Gender Influence on Long-Term Weight Loss and Comorbidities After Laparoscopic Sleeve Gastrectomy and Roux-en-Y Gastric Bypass: a Prospective Study With a 5-Year Follow-up.

Federico Perrone, Emanuela Bianciardi, Domenico Benavoli, Valeria Tognoni, Cinzia Niolu, Alberto Siracusano, Achille L Gaspari, Paolo Gentileschi

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02947412 (Long Term Results After Sleeve Gastrectomy as a Primary Procedure in Obesity Surgery), which is not on this map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02947412 completednot on this map

Long Term Results After Sleeve Gastrectomy as a Primary Procedure in Obesity Surgery

TypeobservationalSponsorSana Klinikum OffenbachRan2007 to 2016Enrolled40ConditionsObesityArmslaparoscopic sleeve gastrectomy
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.

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  5. Sex and gender differences in metabolic dysfunction-associated liver disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Federico PerroneGeneral Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. fed.perrone@gmail.com.
Emanuela BianciardiPsychiatric Unit, Department of System Medicine, University of Rome, Tor Vergata, Italy. emanuelabianciardi@libero.it.
Domenico BenavoliGeneral Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. dobenavoli@yahoo.com.
Valeria TognoniGeneral Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. vtognoni@gmail.com.
Cinzia NioluPsychiatric Unit, Department of System Medicine, University of Rome, Tor Vergata, Italy. niolu@med.uniroma2.it.
Alberto SiracusanoPsychiatric Unit, Department of System Medicine, University of Rome, Tor Vergata, Italy. siracusano@med.uniroma2.it.
Achille L GaspariGeneral Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. gaspari@med.uniroma2.it.
Paolo GentileschiGeneral Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. gentilp@yahoo.com.
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGender might be important in predicting outcomes after bariatric surgery. The aim of the study was to investigate the influence of gender on long-term weight loss and comorbidity improvement after laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB).

methodsA cohort of 304 consecutive patients underwent surgery in 2006-2009: 162 (98 women, 64 men) underwent LSG and 142 (112 women, 30 men) underwent LRYGB. The mean follow-up time was 75.8 ± 8.4 months (range, 60-96 months).

resultsOverall mean (95% CI) reduction in BMI was 23.5 (24.3-22.7) kg/m(2) after 5 years, with no statistical difference between LSG and LRYGB groups (P = 0.94). The overall means ± standard deviations of %EBMIL after 5 years were 78.8 ± 23.5 and 81.6 ± 21.4 in the LSG and LRYGB groups, respectively. Only for LSG group %EBMIL after 24-36 and 60 months differed significantly between male and female patients (P = 0.003 versus P = 0.06 in LRYGB), and 89 versus 90% of patients showed improvements in comorbidities in the LSG and LRYGB groups, respectively. Only two patients (women) were lost to follow-up: 1/162 (0.6%) for LSG at the 4th year and 1/142 (0.7%) for LRYGB to the 5th year.

conclusionsLSG was more effective in obese male than in female patients in terms of %EBMIL, with no difference in comorbidities. LRYGB elicited similar results in both genders in terms of %EBMIL and comorbidities.

Indexed as

Weight LossAdultComorbidityFemaleFollow-Up StudiesGastrectomyGastric BypassHumansLaparoscopyMaleMiddle AgedObesityProspective StudiesSex FactorsBariatric surgeryGastric BypassGenderObesityPredictorsSleeve gastrectomyWeight loss

Identifiers

PMID26033435
OpenAlexW569167601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.