Evidence map›Paper›PMID 26032994›Full record

ArticleActa neurologica Scandinavica2016

Age dependency of ischaemic stroke subtypes and vascular risk factors in western Norway: the Bergen Norwegian Stroke Cooperation Study.

A Nacu, A Fromm, K M Sand, U Waje-Andreassen, L Thomassen, H Naess

Abstract read
In one paragraph

Article in Acta neurologica Scandinavica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Age-Related Risk Factors at the First Stroke Event.Journal of clinical medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A NacuCentre for Neurovascular Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway.
A FrommCentre for Neurovascular Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway.
K M SandCentre for Neurovascular Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway.
U Waje-AndreassenCentre for Neurovascular Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway.
L ThomassenCentre for Neurovascular Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway.
H NaessCentre for Neurovascular Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAge dependency of acute ischaemic stroke aetiology and vascular risk factors have not been adequately evaluated in stroke patients in Norway. Aims of this study were to evaluate how stroke subtypes and vascular risk factors vary with age in a western Norway stroke population. MATERIALS AND

methodsPatients aged 15-100 years consecutively admitted to our neurovascular centre with acute ischaemic stroke between 2006 and 2012 were included. The study population was categorized as young (15-49 years), middle-aged (50-74 years) or elderly (≥ 75 years). Stroke aetiology was defined by TOAST criteria. Risk factors and history of cardiovascular disease were recorded.

resultsIn total, 2484 patients with acute cerebral infarction were included: 1418 were males (57.3%). Mean age was 70.8 years (SD ± 14.9), 228 patients were young, 1126 middle-aged, and 1130 were elderly. The proportion of large-artery atherosclerosis and of small-vessel occlusion was highest among middle-aged patients. The proportion of cardioembolism was high at all ages, especially among the elderly. The proportion of stroke of other determined cause was highest among young patients. Some risk factors (diabetes mellitus, active smoking, angina pectoris, prior stroke and peripheral artery disease) decreased among the elderly. The proportions of several potential causes increased with age.

conclusionThe proportion of stroke subtypes and vascular risk factors are age dependent. Age 50-74 years constitutes the period in life where cardiovascular risk factors become manifest and stroke subtypes change.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsAtherosclerosisBrain IschemiaCerebral InfarctionCerebral Small Vessel DiseasesEmbolismFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNorwayagecardiovascular diseaseischaemic strokestroke aetiologystroke subtypestrial of org 10172 in acute stroke treatmentvascular risk factors

Identifiers

PMID26032994
PMCPMC4744685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.