Evidence map›Paper›PMID 26032267›Full record

ArticleCell research2015

Cancer immunotherapy: exploiting neoepitopes.

Michael Platten, Rienk Offringa

Abstract readComment
In one paragraph

Article in Cell research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Clinical and Translational Advances in Glioma Immunotherapy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Review
  2. Article
  3. Review
  4. Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers.Clinical cancer research : an official journal of the American Association for Cancer Research · 2018
    Article
  5. Review
  6. Vaccine Strategies in Gliomas.Current treatment options in neurology · 2018
    Review
  7. Article
  8. Review
  9. Concepts in glioma immunotherapy.Cancer immunology, immunotherapy : CII · 2016
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michael Platten1] DKTK Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center, Heidelberg, Germany [2] Neurology Clinic, University Hospital Heidelberg and National Center for Tumor Diseases, Heidelberg, Germany.
Rienk Offringa1] Dept. Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center, Heidelberg, Germany [2] European Pancreas Center, Surgery Clinic, University Hospital Heidelberg, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of cancer vaccines has long been hampered by insufficient definition of tumor-specific antigens. A recent study by Kreiter et al. published in Nature has provided a blueprint for a patient-tailored approach to develop individualized RNA vaccines.

Indexed as

AnimalsEpitopes, T-LymphocyteFemaleHistocompatibility Antigens Class IIHumansImmunotherapyMelanoma, ExperimentalMutationEpitopes, T-LymphocyteHistocompatibility Antigens Class II

Identifiers

PMID26032267
PMCPMC4528051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.