Evidence map›Paper›PMID 26032207›Full record

ArticleJournal of musculoskeletal & neuronal interactions2015

Gastrocnemius medialis muscle architecture and physiological cross sectional area in adult males with Duchenne muscular dystrophy.

C I Morse, J Smith, A Denny, J Tweedale, N D Searle

Open access · greenAbstract read
In one paragraph

Article in Journal of musculoskeletal & neuronal interactions, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C I MorseInstitute for Performance Research, Department of Exercise and Sport Science, Manchester Metropolitan University Cheshire, CW1 5DU, UK.
J SmithInstitute for Performance Research, Department of Exercise and Sport Science, Manchester Metropolitan University Cheshire, CW1 5DU, UK.
A DennyInstitute for Performance Research, Department of Exercise and Sport Science, Manchester Metropolitan University Cheshire, CW1 5DU, UK.
J TweedaleInstitute for Performance Research, Department of Exercise and Sport Science, Manchester Metropolitan University Cheshire, CW1 5DU, UK.
N D SearleInstitute for Performance Research, Department of Exercise and Sport Science, Manchester Metropolitan University Cheshire, CW1 5DU, UK.
Manchester Metropolitan University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe muscle size and architecture of the gastrocnemius medialis (GM) muscle in eleven adult males with Duchenne Muscular Dystrophy (DMD, age 24.5±5.4 years), and a control group of eleven males without DMD (CTRL, age 22.1±0.9 years).

methodsGM anatomical cross sectional area (ACSA), volume (VOL), physiological cross sectional area (PCSA), fascicle length (Lf) and pennation angle (θ) were assessed using B-Mode Ultrasonography. GM ACSA was measured at 25, 50 and 75% of muscle length (Lm), from which VOL was calculated. At 50% of Lm, sagittal plane images were analysed to determine GM Lf and θ. GM PCSA was calculated as: VOL/Lf. The ratio of Lf and Lm was also calculated.

resultsGM ACSA at 50% Lm, VOL and PCSA were smaller in DMD males compared to CTRL males by 36, 47 and 43%, respectively (P<0.01). There were no differences in Lf and θ. GM Lm was 29% shorter in DMD compared to CTRL. Lf/Lm was 29% longer in DMD (P<0.01).

conclusionsUnlike previous data in children with DMD, our results show significant atrophy in adult males with DMD, and no change in Lf or θ. The shorter Lm may have implications for joint flexibility.

Indexed as

AdultAgingAnatomy, Cross-SectionalBody HeightBody WeightHumansMaleMuscle, SkeletalMuscular Dystrophy, DuchenneUltrasonographyYoung Adult

Identifiers

PMID26032207
PMCPMC5133718
OpenAlexW1011493942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.