Evidence map›Paper›PMID 26032204›Full record

ArticleJournal of musculoskeletal & neuronal interactions2015

Reactions of the rat musculoskeletal system to compressive spinal cord injury (SCI) and whole body vibration (WBV) therapy.

A Schwarz, C Pick, R Harrach, G Stein, H Bendella, O Ozsoy, U Ozsoy, E Schoenau, P Jaminet, L Sarikcioglu and 2 more

Abstract read
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In one paragraph

Article in Journal of musculoskeletal & neuronal interactions, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

A SchwarzDepartment of Anatomy I, University of Cologne, Germany.
C PickDepartment of Anatomy I, University of Cologne, Germany.
R HarrachDepartment of Anatomy I, University of Cologne, Germany.
G SteinDepartment of Orthopedics and Trauma Surgery, University of Cologne, Germany.
H BendellaDepartment of Neurosurgery, Hospital Merheim, University of Witten-Herdecke, Cologne, Germany.
O OzsoyDepartment of Physiology, Akdeniz University of Antalya, Turkey.
U OzsoyDepartment of Anatomy, Akdeniz University of Antalya, Turkey.
E SchoenauChildren's Hospital, University of Cologne, Germany.
P JaminetDepartment of Hand-, Plastic-, and Reconstructive Surgery with Burn Unit, BG- Trauma Centre, University of Tuebingen, Germany.
L SarikciogluDepartment of Anatomy, Akdeniz University of Antalya, Turkey.
S DunlopSchool of Animal Biology, The University of Western Australia, Australia.
D N AngelovDepartment of Anatomy I, University of Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic spinal cord injury (SCI) causes a loss of locomotor function with associated compromise of the musculo-skeletal system. Whole body vibration (WBV) is a potential therapy following SCI, but little is known about its effects on the musculo-skeletal system. Here, we examined locomotor recovery and the musculo-skeletal system after thoracic (T7-9) compression SCI in adult rats. Daily WBV was started at 1, 7, 14 and 28 days after injury (WBV1-WBV28 respectively) and continued over a 12-week post-injury period. Intact rats, rats with SCI but no WBV (sham-treated) and a group that received passive flexion and extension (PFE) of their hind limbs served as controls. Compared to sham-treated rats, neither WBV nor PFE improved motor function. Only WBV14 and PFE improved body support. In line with earlier studies we failed to detect signs of soleus muscle atrophy (weight, cross sectional diameter, total amount of fibers, mean fiber diameter) or bone loss in the femur (length, weight, bone mineral density). One possible explanation is that, despite of injury extent, the preservation of some axons in the white matter, in combination with quadripedal locomotion, may provide sufficient trophic and neuronal support for the musculoskeletal system.

Indexed as

AnimalsAtrophyAxonsBone and BonesFemaleFemurHindlimbLocomotionMuscle, SkeletalMusculoskeletal SystemPhysical Therapy ModalitiesPsychomotor PerformanceRatsRats, WistarRecovery of FunctionSpinal Cord Compression

Identifiers

PMID26032204
PMCPMC5133715

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.