Evidence map›Paper›PMID 26031971›Full record

ArticleClinical medicine (London, England)2015

Comparison of ESC and NICE guidelines for patients with suspected coronary artery disease: evaluation of the pre-test probability risk scores in clinical practice.

Ozan M Demir, Peter Dobson, Nikolaos D Papamichael, Jonathan Byrne, Sven Plein, Khaled Alfakih

Abstract readComparative Study
In one paragraph

Article in Clinical medicine (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Ozan M DemirDepartment of Cardiology, University Hospital Lewisham, London, UK.
Peter DobsonDepartment of Cardiology, University Hospital Lewisham, London, UK.
Nikolaos D PapamichaelDepartment of Cardiology, University Hospital Lewisham, London, UK.
Jonathan ByrneDepartment of Cardiology, King's College Hospital, London, UK.
Sven PleinMultidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds, UK.
Khaled AlfakihDepartment of Cardiology, University Hospital Lewisham, London, UK, and Department of Cardiology, King's College Hospital, London, UK khaled.alfakih@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Society of Cardiology (ESC) and UK National Institute for Health and Care Excellence (NICE) have recently published guidelines for investigating patients with suspected coronary artery disease (CAD). Both provide a risk score (RS) to assess the pre-test probability for CAD to guide clinicians to undertake the most effective investigation. The aim of the study was to establish whether there is a difference between the two RS models. We retrospectively reviewed records of 479 patients who presented to a UK district general hospital with chest pain between August 2011 and April 2013. The RS was calculated using ESC and NICE guidelines and compared. From the 479 patients, 277 (58%) were male and the mean age was 60 years. The mean RS was greater using NICE guidelines compared with ESC (66.3 vs 47.9%, 18.4% difference; p<0.0001). The difference in mean RS was smaller in patients with typical chest pain (13.0%). When we divided the cohort based on NICE criteria into 'high'- and 'low'-risk groups, the difference in the mean RS was 24.3% in the 'high'-risk group (p<0.001) compared with 2.8% in the 'low'-risk group. The UK NICE risk score model overestimates risk compared with the ESC model.

Indexed as

Health Status IndicatorsAgedAngina PectorisCoronary AngiographyCoronary Artery DiseaseFemaleGuideline AdherenceHumansMaleMiddle AgedModels, StatisticalPractice Guidelines as TopicRetrospective Studiesanginacardiac CTIschemic heart diseasenon-invasive functional testsstress echocardiogram

Identifiers

PMID26031971
PMCPMC4953105

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.