ArticleBehavioral neuroscience2015
Memory-enhancing amygdala stimulation elicits gamma synchrony in the hippocampus.
Article in Behavioral neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05065450 (Mechanisms of Amygdala-Mediated Memory Enhancement in Humans), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mechanisms of Amygdala-Mediated Memory Enhancement in Humans
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Structural and functional neural adaptations in obstructive sleep apnea: An activation likelihood estimation meta-analysis.Neuroscience and biobehavioral reviews · 2016Pooled it
- Direct electrical stimulation of the amygdala enhances declarative memory in humans.Proceedings of the National Academy of Sciences of the United States of America · 2018Trial
- Direct electrical stimulation of the human amygdala enhances recognition memory for objects but not scenes.Communications biology · 2026Article
- Novelty, Ecological Relevance, and Sexual Receptivity Modulate Neuronal Interactions between the Amygdala and Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Possible Role of Dopamine in the Enhancement of Intrahippocampal Arc Protein Expression Induced by Post-Learning Noradrenergic Stimulation of the Basolateral Amygdala.International journal of molecular sciences · 2026Article
- Identification of plasma biomarkers in a PTZ-induced Sudden Unexpected Death-like model through integrated proteomics and metabolomics methods.Frontiers in medicine · 2026Article
- Article
- Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala.bioRxiv : the preprint server for biology · 2025Article
- Visualizing functional network connectivity differences using an explainable machine-learning method.Physiological measurement · 2025Article
- Quantitative simulation of near-infrared light treatment for Alzheimer's disease using patient-individualized optical-parametric phantoms.Neurophotonics · 2025Article
- Memory capacity and prioritization in female mice.Scientific reports · 2023Article
- The amygdala mediates the facilitating influence of emotions on memory through multiple interacting mechanisms.Neurobiology of stress · 2023Review
- Aversive memory formation in humans involves an amygdala-hippocampus phase code.Nature communications · 2022Article
- Amygdala-hippocampal interactions in synaptic plasticity and memory formation.Neurobiology of learning and memory · 2021Review
- Optogenetic stimulation of the basolateral amygdala accelerates acquisition of object-context associations.Behavioral neuroscience · 2021Article
- Modulation of Human Memory by Deep Brain Stimulation of the Entorhinal-Hippocampal Circuitry.Neuron · 2020Review
- Closed-loop control of gamma oscillations in the amygdala demonstrates their role in spatial memory consolidation.Nature communications · 2019Article
- The Science of Auricular Microsystem Acupuncture: Amygdala Function in Psychiatric, Neuromusculoskeletal, and Functional Disorders.Medical acupuncture · 2019Article
- Optogenetic Stimulation of the Basolateral Amygdala Increased Theta-Modulated Gamma Oscillations in the Hippocampus.Frontiers in behavioral neuroscience · 2019Article
- Specificity of Primate Amygdalar Pathways to Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Activation of the amygdala either during emotional arousal or by direct stimulation is thought to enhance memory in part by modulating plasticity in the hippocampus. However, precisely how the amygdala influences hippocampal activity to improve memory remains unclear. In the present study, brief electrical stimulation delivered to the basolateral complex of the amygdala (BLA) following encounters with some novel objects led to better memory for those objects 1 day later. Stimulation also elicited field-field and spike-field CA3-CA1 synchrony in the hippocampus in the low gamma frequency range (30-55 Hz), a range previously associated with spike timing and good memory. In addition, the hippocampal spiking patterns observed during BLA stimulation reflected recent patterns of activity in the hippocampus. Thus, the results indicate that amygdala activation can prioritize memory consolidation of specific object encounters by coordinating the precise timing of CA1 membrane depolarization with incoming CA3 spikes to initiate long-lasting spike-timing dependent plasticity at putative synapses between recently active neurons.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.