Evidence map›Paper›PMID 26030357›Full record

ArticlePloS one2015

Cognitive alexithymia is associated with the degree of risk for psychosis.

Jorien van der Velde, Marte Swart, Sophie van Rijn, Lisette van der Meer, Lex Wunderink, Durk Wiersma, Lydia Krabbendam, Richard Bruggeman, André Aleman

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
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  7. Article
  8. The percentage and clinical correlates of alexithymia in stable patients with schizophrenia.European archives of psychiatry and clinical neuroscience · 2023
    Article
  9. Article
  10. Social-specific impairment of negative emotion perception in alexithymia.Social cognitive and affective neuroscience · 2022
    Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Jorien van der VeldeNeuroimaging Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Academy for sociale studies, Hanze University of Apllied Sciences, Groningen, The Netherlands.
Marte SwartLentis, Center for Mental Healthcare, Groningen, The Netherlands; Rob Giel Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Sophie van RijnClinical Child and Adolescent Studies, Leiden University, Leiden, The Netherlands.
Lisette van der MeerLentis, Center for Mental Healthcare, Groningen, The Netherlands.
Lex WunderinkDepartment of Psychosis studies, Mental Health Care Friesland, Leeuwarden, The Netherlands.
Durk WiersmaRob Giel Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Lydia KrabbendamRob Giel Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Richard BruggemanDepartment of Educational Neuroscience, Faculty of Psychology and Education, VU University Amsterdam, Amsterdam, The Netherlands.
André AlemanNeuroimaging Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
University of Groningen · NLGGZ Friesland · NLHanze University of Applied Sciences · NLLeiden University · NLLentis · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alexithymia is a personality construct denoting emotion processing problems. It has been suggested to encompass two dimensions: a cognitive and affective dimension. The cognitive dimension is characterized by difficulties in identifying, verbalizing and analyzing emotions, while the affective dimension reflects the level of emotional arousal and imagination. Alexithymia has been previously proposed as a risk factor for developing psychosis. More specifically, the two alexithymia dimensions might be differentially related to the vulnerability for psychosis. Therefore, we examined the two dimensions of alexithymia, measured with the BVAQ in 94 siblings of patients with schizophrenia, 52 subjects at ultra-high risk (UHR) for developing psychosis, 38 patients with schizophrenia and 109 healthy controls. The results revealed that siblings and patients had higher levels of cognitive alexithymia compared to controls. In addition, subjects at UHR for psychosis had even higher levels of cognitive alexithymia compared to the siblings. The levels of affective alexithymia in siblings and patients were equal to controls. However, UHR individuals had significantly lower levels of affective alexithymia (i.e. higher levels of emotional arousal and fantasizing) compared to controls. Alexithymia was further related to subclinical levels of negative and depressive symptoms. These findings indicate that alexithymia varies parametrically with the degree of risk for psychosis. More specifically, a type-II alexithymia pattern, with high levels of cognitive alexithymia and normal or low levels of affective alexithymia, might be a vulnerability factor for psychosis.

Indexed as

AdultAffective SymptomsFemaleHumansMalePsychotic DisordersRisk FactorsSchizophreniaYoung Adult

Identifiers

PMID26030357
PMCPMC4451258
OpenAlexW1572047407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.