Evidence map›Paper›PMID 26029905›Full record

ArticlePloS one2015

Contrast Enhancement of the Right Ventricle during Coronary CT Angiography--Is It Necessary?

Madeleine Kok, Bas L J H Kietselaer, Casper Mihl, Sibel Altintas, Estelle C Nijssen, Joachim E Wildberger, Marco Das

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Madeleine KokDepartment of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands; CARIM Cardio Vascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.
Bas L J H KietselaerDepartment of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands; CARIM Cardio Vascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Casper MihlDepartment of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands; CARIM Cardio Vascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.
Sibel AltintasCARIM Cardio Vascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Estelle C NijssenDepartment of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands.
Joachim E WildbergerDepartment of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands; CARIM Cardio Vascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.
Marco DasDepartment of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands; CARIM Cardio Vascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt is unclear if prolonged contrast media injection, to improve right ventricular visualization during coronary CT angiography, leads to increased detection of right ventricle pathology. The purpose of this study was to evaluate right ventricle enhancement and subsequent detection of right ventricle disease during coronary CT angiography. MATERIALS AND

methods472 consecutive patients referred for screening coronary CT angiography were retrospectively evaluated. Every patient underwent multidetector-row CT of the coronary arteries: 128x 0.6mm coll., 100-120kV, rot. time 0.28s, ref. mAs 350 and received an individualized (P3T) contrast bolus injection of iodinated contrast medium (300 mgI/ml). Patient data were analyzed to assess right ventricle enhancement (HU) and right ventricle pathology. Image quality was defined good when right ventricle enhancement >200HU, moderate when 140-200HU and poor when <140HU.

resultsGood image quality was found in 372 patients, moderate in 80 patients and poor in 20 patients. Mean enhancement of the right ventricle cavity was 268HU±102. Patients received an average bolus of 108±24 ml at an average peak flow rate of 6.1±2.2 ml/s. In only three out of 472 patients (0.63%) pathology of the right ventricle was found (dilatation) No other right ventricle pathology was detected.

conclusionRight ventricle pathology was detected in three out of 472 patients; the dilatation observed in these three cases may have been picked up even without dedicated enhancement of the right ventricle. Based on our findings, right ventricle enhancement can be omitted during screening coronary CT angiography.

Indexed as

AgedContrast MediaCoronary AngiographyCoronary VesselsFemaleHeart VentriclesHumansInjections, IntravenousMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedContrast Media

Identifiers

PMID26029905
PMCPMC4451990

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.