ArticleJournal of the American Chemical Society2015
Total Synthesis of (-)-Nodulisporic Acid D.
Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 54 citations in OpenAlex.
- Total Synthesis of (+)-Shearilicine.Journal of the American Chemical Society · 2023Article
- Synthesis of rearranged indole diterpenes of the paxilline type.Natural product reports · 2022Review
- Total Synthesis of Shearinines D and G: A Convergent Approach to Indole Diterpenoids.Angewandte Chemie (International ed. in English) · 2022Article
- New Methods and Strategies in the Synthesis of Terpenoid Natural Products.Accounts of chemical research · 2021Review
- Catalytic enantioselective conjugate addition en route to paxilline indoloterpenoids.Tetrahedron · 2019Article
- Twelve-Step Asymmetric Synthesis of (-)-Nodulisporic Acid C.Journal of the American Chemical Society · 2018Article
- Total Synthesis of (-)-Nodulisporic Acids D, C, and B: Evolution of a Unified Synthetic Strategy.Journal of the American Chemical Society · 2018Article
- Total synthesis of architecturally complex indole terpenoids: strategic and tactical evolution.The Journal of antibiotics · 2018Review
- Indole diterpenoid natural products as the inspiration for new synthetic methods and strategies.Chemical science · 2017Review
- Type II Anion Relay Chemistry: Conformational Constraints To Achieve Effective [1,5]-Vinyl Brook Rearrangements.Journal of the American Chemical Society · 2017Article
- Organic synthesis in the Smith Group: a personal selection of a dozen lessons learned at the University of Pennsylvania.The Journal of antibiotics · 2016Article
- Chemistry: Why synthesize?Nature · 2015Article
- A Concise Approach to Paxilline Indole Diterpenes.Journal of the American Chemical Society · 2015Article
- Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast.Journal of the American Chemical Society · 2015Article
- Asymmetric Total Synthesis of the Indole Diterpene Alkaloid Paspaline.The Journal of organic chemistry · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
A convergent total synthesis of the architecturally complex indole diterpenoid (-)-nodulisporic acid D has been achieved. Key synthetic transformations include vicinal difunctionalization of an advanced α,β-unsaturated aldehyde to form the E,F-trans-fused 5,6-ring system of the eastern hemisphere and a cascade cross-coupling/indolization protocol leading to the CDE multisubstituted indole core.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.