Evidence map›Paper›PMID 26029737›Full record

ArticleExtreme Mechanics Letters2014

Quantitative Biomechanics of Healthy and Diseased Human Red Blood Cells using Dielectrophoresis in a Microfluidic System.

E Du, Ming Dao, Subra Suresh

Abstract read
In one paragraph

Article in Extreme Mechanics Letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Methods to mechanically perturb and characterize GUV-based minimal cell models.Computational and structural biotechnology journal · 2023
    Review
  8. Article
  9. Article
  10. Isolation method ofBiomedical optics express · 2022
    Article
  11. Article
  12. Review
  13. Lab on a chip · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Mechanical fatigue of human red blood cells.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

E DuDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Ming DaoDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Subra SureshDepartment of Biomedical Engineering and Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA 15213.

Funding

Multiscale Modeling of Sickle Cell Anemia: Methods and ValidationU01HL114476 · NHLBI · BROWN UNIVERSITY · PI DAO, MING, HIGGINS, JOHN MATTHEW · 2013 to 2017
$3.9M
Multiscale Modeling and Parallel Simulations of Blood Flow in Cerebral Malaria anR01HL094270 · NHLBI · BROWN UNIVERSITY · PI KARNIADAKIS, GEORGE, SURESH, SUBRA · 2009 to 2011
$1.8M
NHLBI NIH HHS R01 HL094270NHLBI NIH HHS U01 HL114476
6 · The paper itself

Abstract

We present an experimental method to quantitatively characterize the mechanical properties of a large number of biological cells by introducing controlled deformation through dielectrophoresis in a microfluidic device. We demonstrate the capability of this technique by determining the force versus deformation characteristics of healthy human red blood cells (RBCs) and RBCs infected

Indexed as

cell deformabilitydielectrophoresisforcemalaria

Identifiers

PMID26029737
PMCPMC4445737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.