Evidence map›Paper›PMID 26029488›Full record

ArticleHealth psychology and behavioral medicine

Chronic Fatigue Syndrome and Myalgic Encephalomyelitis: Toward An Empirical Case Definition.

Leonard A Jason, Bobby Kot, Madison Sunnquist, Abigail Brown, Meredyth Evans, Rachel Jantke, Yolonda Williams, Jacob Furst, Suzanne D Vernon

Abstract read
In one paragraph

Article in Health psychology and behavioral medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. [Post-corona fatigue-a familiar picture in a new guise?]Der Onkologe : Organ der Deutschen Krebsgesellschaft e.V · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leonard A JasonDePaul University.
Bobby KotDePaul University.
Madison SunnquistDePaul University.
Abigail BrownDePaul University.
Meredyth EvansDePaul University.
Rachel JantkeDePaul University.
Yolonda WilliamsDePaul University.
Jacob FurstDePaul University.
Suzanne D VernonSolve ME/CFS Initiative.

Funding

A prospective study of CFS following infectious mononucleosis in college studentsR01AI105781 · NIAID · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI JASON, LEONARD A, KATZ, BEN Z. · 2014 to 2018
$3.4M
Pediatric CFS in a Community-Based SampleR01HD072208 · NICHD · DE PAUL UNIVERSITY · PI JASON, LEONARD A · 2013 to 2017
$2.0M
NIAID NIH HHS R01 AI105781NICHD NIH HHS R01 HD072208
6 · The paper itself

Abstract

Current case definitions of Myalgic Encephalomyelitis (ME) and chronic fatigue syndrome (CFS) have been based on consensus methods, but empirical methods could be used to identify core symptoms and thereby improve the reliability. In the present study, several methods (i.e., continuous scores of symptoms, theoretically and empirically derived cut off scores of symptoms) were used to identify core symptoms best differentiating patients from controls. In addition, data mining with decision trees was conducted. Our study found a small number of core symptoms that have good sensitivity and specificity, and these included fatigue, post-exertional malaise, a neurocognitive symptom, and unrefreshing sleep. Outcomes from these analyses suggest that using empirically selected symptoms can help guide the creation of a more reliable case definition.

Indexed as

biomarkerscase definitionschronic fatigue syndromeMyalgic Encephalomyelitits

Identifiers

PMID26029488
PMCPMC4443921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.