ReviewFrontiers in microbiology2015
Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal.
Review in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 67 citations in OpenAlex.
- Influence of Cellulose Particles on Streptomyces spp. Growth, Morphology, and Metabolite Spectrum.Microbial biotechnology · 2026Article
- A statistical approach to enhance the productivity of Streptomyces baarensis MH-133 for bioactive compounds.Synthetic and systems biotechnology · 2024Article
- Biodiversity and Bioactive Potential of Actinomycetes from Unexplored High Altitude Regions of Kargil, India.Indian journal of microbiology · 2024Article
- Draft genome sequence of potato crop bacterial isolates and nanoparticles-intervention for the induction of secondary metabolites biosynthesis.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Small molecule inducers of actinobacteria natural product biosynthesis.Journal of industrial microbiology & biotechnology · 2023Review
- Crystal structures of free and ligand-bound forms of the TetR/AcrR-like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism.The FEBS journal · 2023Article
- Insights intoEngineering in life sciences · 2023Article
- Tunable population dynamics in a synthetic filamentous coculture.MicrobiologyOpen · 2022Article
- Recently Discovered Secondary Metabolites fromMolecules (Basel, Switzerland) · 2022Review
- HAS 1: A natural product from soil-isolatedFrontiers in pharmacology · 2022Article
- Application of Bio-Friendly Formulations of Chitinase-ProducingJournal of fungi (Basel, Switzerland) · 2021Article
- Iron competition triggers antibiotic biosynthesis in Streptomyces coelicolor during coculture with Myxococcus xanthus.The ISME journal · 2020Article
- Streptomyces sp. VN1, a producer of diverse metabolites including non-natural furan-type anticancer compound.Scientific reports · 2020Article
- The antibiotic crisis: How bacterial predators can help.Computational and structural biotechnology journal · 2020Review
- Editorial: Actinobacteria: Prolific Producers of Bioactive Metabolites.Frontiers in microbiology · 2020Article
- Biocontrol of Cereal Crop Diseases Using Streptomycetes.Pathogens (Basel, Switzerland) · 2019Review
- Evaluation of in-vitro methods to select effective streptomycetes against toxigenic fusaria.PeerJ · 2019Article
- Diversity, Ecology, and Prevalence of Antimicrobials in Nature.Frontiers in microbiology · 2019Review
- Antifungal, Plant Growth-Promoting, and Genomic Properties of an Endophytic ActinobacteriumFrontiers in microbiology · 2019Article
- Visual and Microscopic Evaluation of Streptomyces Developmental Mutants.Journal of visualized experiments : JoVE · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emergence of antibiotic resistant pathogens is changing the way scientists look for new antibiotic compounds. This race against the increased prevalence of multi-resistant strains makes it necessary to expedite the search for new compounds with antibiotic activity and to increase the production of the known. Here, we review a variety of new scientific approaches aiming to enhance antibiotic production in Streptomyces. These include: (i) elucidation of the signals that trigger the antibiotic biosynthetic pathways to improve culture media, (ii) bacterial hormone studies aiming to reproduce intra and interspecific communications resulting in antibiotic burst, (iii) co-cultures to mimic competition-collaboration scenarios in nature, and (iv) the very recent in situ search for antibiotics that might be applied in Streptomyces natural habitats. These new research strategies combined with new analytical and molecular techniques should accelerate the discovery process when the urgency for new compounds is higher than ever.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.