Evidence map›Paper›PMID 26029157›Full record

ReviewFrontiers in neurology2015

Owls and larks in mice.

Martina Pfeffer, Helmut Wicht, Charlotte von Gall, Horst-Werner Korf

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Clocking In, Working Out: Circadian Regulation of Exercise Physiology.Trends in endocrinology and metabolism: TEM · 2019
    Review
  10. Two sides of a coin: ecological and chronobiological perspectives of timing in the wild.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
  11. The Role of the Melatoninergic System in Light-Entrained Behavior of Mice.International journal of molecular sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martina PfefferDr. Senckenbergische Anatomie II, Fachbereich Medizin der Goethe-Universität , Frankfurt am Main , Germany ; Dr. Senckenbergisches Chronomedizinisches Institut, Fachbereich Medizin der Goethe-Universität , Frankfurt am Main , Germany.
Helmut WichtDr. Senckenbergische Anatomie II, Fachbereich Medizin der Goethe-Universität , Frankfurt am Main , Germany ; Dr. Senckenbergisches Chronomedizinisches Institut, Fachbereich Medizin der Goethe-Universität , Frankfurt am Main , Germany.
Charlotte von GallInstitut für Anatomie II, Fachbereich Medizin, Heinrich Heine Universität , Düsseldorf , Germany.
Horst-Werner KorfDr. Senckenbergische Anatomie II, Fachbereich Medizin der Goethe-Universität , Frankfurt am Main , Germany ; Dr. Senckenbergisches Chronomedizinisches Institut, Fachbereich Medizin der Goethe-Universität , Frankfurt am Main , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans come in different chronotypes and, particularly, the late chronotype (the so-called owl) has been shown to be associated with several health risks. A number of studies show that laboratory mice also display various chronotypes. In mice as well as in humans, the chronotype shows correlations with the period length and rhythm stability. In addition, some mouse models for human diseases show alterations in their chronotypic behavior, which are comparable to those humans. Thus, analysis of the behavior of mice is a powerful tool to unravel the molecular and genetic background of the chronotype and the prevalence of risks and diseases that are associated with it. In this review, we summarize the correlation of chronotype with free-running period length and rhythm stability in inbred mouse strains, in mice with a compromised molecular clockwork, and in a mouse model for neurodegeneration.

Indexed as

activity rhythmschronobiologychronotypecircadian rhythmsneurodegenerationstability

Identifiers

PMID26029157
PMCPMC4432671

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.