ReviewFrontiers in aging neuroscience2015
A succinct overview of virtual reality technology use in Alzheimer's disease.
Review in Frontiers in aging neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 73 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Use of Virtual Reality to Improve Spatial Orientation in Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review.Current Alzheimer research · 2024Pooled it
- Addressing Cognitive Function and Psychological Well-Being in Chronic Kidney Disease: A Systematic Review on the Use of Technology-Based Interventions.International journal of environmental research and public health · 2023Pooled it
- A systematic review: Virtual-reality-based techniques for human exercises and health improvement.Frontiers in public health · 2023Pooled it
- Effect of virtual reality exercise on interventions for patients with Alzheimer's disease: A systematic review.Frontiers in psychiatry · 2022Pooled it
- Brain-Computer Interfaces Systems for Upper and Lower Limb Rehabilitation: A Systematic Review.Sensors (Basel, Switzerland) · 2021Pooled it
- Intelligent Sensing Technologies for the Diagnosis, Monitoring and Therapy of Alzheimer's Disease: A Systematic Review.Sensors (Basel, Switzerland) · 2021Pooled it
- The Role of Virtual Reality in Improving Health Outcomes for Community-Dwelling Older Adults: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Use of Immersive Virtual Reality in the Assessment and Treatment of Alzheimer's Disease: A Systematic Review.Journal of Alzheimer's disease : JAD · 2020Pooled it
- Usability Issues of Clinical and Research Applications of Virtual Reality in Older People: A Systematic Review.Frontiers in human neuroscience · 2020Pooled it
- The effectiveness of virtual reality for people with mild cognitive impairment or dementia: a meta-analysis.BMC psychiatry · 2019Pooled it
- Virtual reality intervention for visual perception in schizophrenia-a single blind pilot randomized controlled trial.BMC psychiatry · 2025Trial
- Immersive virtual reality for cognitive rehabilitation in patients who had a stroke: study protocol for a randomised controlled trial.BMJ open · 2026Article
- Wearable EEG devices in the detection of mild cognitive impairment: a systematic review.NPJ digital medicine · 2026Article
- Digital Therapeutics for Alzheimer's and Parkinson's Diseases: Current Trends and Future Perspectives.Medicinal research reviews · 2026Review
- Digital Technology in Cognitive Decline: Bibliometric and Visualization Study.Current Alzheimer research · 2026Review
- Article
- Anticipatory reaching motor behavior characterizes patients within the Alzheimer's disease continuum in a virtual reality environment.Alzheimer's research & therapy · 2025Article
- The interactive use of augmented reality for educating the elderly on common age-related eye disease.BMC geriatrics · 2025Article
- Assessing Cognition in Kidney Failure Using Virtual Reality Technology: A Clinical Research Protocol.Canadian journal of kidney health and disease · 2025Article
- Rethinking neuropsychological test validity in dementia assessment: a critical review in the age of neuroimaging and digital markers.Frontiers in human neuroscience · 2025Review
13 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We provide a brief review and appraisal of recent and current virtual reality (VR) technology for Alzheimer's disease (AD) applications. We categorize them according to their intended purpose (e.g., diagnosis, patient cognitive training, caregivers' education, etc.), focus feature (e.g., spatial impairment, memory deficit, etc.), methodology employed (e.g., tasks, games, etc.), immersion level, and passive or active interaction. Critical assessment indicates that most of them do not yet take full advantage of virtual environments with high levels of immersion and interaction. Many still rely on conventional 2D graphic displays to create non-immersive or semi-immersive VR scenarios. Important improvements are needed to make VR a better and more versatile assessment and training tool for AD. The use of the latest display technologies available, such as emerging head-mounted displays and 3D smart TV technologies, together with realistic multi-sensorial interaction devices, and neuro-physiological feedback capacity, are some of the most beneficial improvements this mini-review suggests. Additionally, it would be desirable that such VR applications for AD be easily and affordably transferable to in-home and nursing home environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.