ArticleFrontiers in neuroanatomy2015
Cytoarchitectonic mapping of the human brain cerebellar nuclei in stereotaxic space and delineation of their co-activation patterns.
Article in Frontiers in neuroanatomy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Functional brain alterations in acute sleep deprivation: An activation likelihood estimation meta-analysis.Sleep medicine reviews · 2019Pooled it
- Investigation of cerebellar structure and static and dynamic functional connectivity in cervical spondylotic myelopathy patients.Neuroradiology · 2026Article
- Asymmetric scaling of cerebellar cortex and deep nuclei reshapes input-output architecture across primates.Research square · 2026Article
- Nonuniform scaling of cerebellar cortical-nuclear architecture across primates revealed by cross-species atlases.bioRxiv : the preprint server for biology · 2026Article
- The volume of the subthalamic nucleus in spinocerebellar ataxia type 3: potential relevance for the clinical phenotype and treatment of parkinsonian symptoms with deep brain stimulation.Journal of neurology · 2024Article
- Clinical Heterogeneity of Essential Tremor: Understanding Neural Substrates of Action Tremor Subtypes.Cerebellum (London, England) · 2024Review
- The Cerebellum's Orchestra: Understanding the Functional Connectivity of Its Lobes and Deep Nuclei in Coordination and Integration of Brain Networks.Tomography (Ann Arbor, Mich.) · 2023Article
- Visualizing the deep cerebellar nuclei using quantitative susceptibility mapping: An application in healthy controls, Parkinson's disease patients and essential tremor patients.Human brain mapping · 2023Article
- Dynamic causal modeling of neural responses to an orofacial pneumotactile velocity array.Neuroimage. Reports · 2022Article
- High-resolution mapping and digital atlas of subcortical regions in the macaque monkey based on matched MAP-MRI and histology.NeuroImage · 2021Article
- Catecholaminergic Innervation of the Lateral Nucleus of the Cerebellum Modulates Cognitive Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Cerebellar nuclei evolved by repeatedly duplicating a conserved cell-type set.Science (New York, N.Y.) · 2020Article
- Article
- The supplementary motor area syndrome and the cerebellar mutism syndrome: a pathoanatomical relationship?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- Resistance, vulnerability and resilience: A review of the cognitive cerebellum in aging and neurodegenerative diseases.Neurobiology of learning and memory · 2020Review
- Cerebellar D1DR-expressing neurons modulate the frontal cortex during timing tasks.Neurobiology of learning and memory · 2020Article
- Advanced Sectioned Images of a Cadaver Head with Voxel Size of 0.04 mm.Journal of Korean medical science · 2019Article
- Functional Outcomes of Cerebellar Malformations.Frontiers in cellular neuroscience · 2019Review
- Dopamine DBiological psychiatry · 2018Article
- Uncovering specific changes in network wiring underlying the primate cerebrotype.Brain structure & function · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The cerebellar nuclei are involved in several brain functions, including the modulation of motor and cognitive performance. To differentiate their participation in these functions, and to analyze their changes in neurodegenerative and other diseases as revealed by neuroimaging, stereotaxic maps are necessary. These maps reflect the complex spatial structure of cerebellar nuclei with adequate spatial resolution and detail. Here we report on the cytoarchitecture of the dentate, interposed (emboliform and globose) and fastigial nuclei, and introduce 3D probability maps in stereotaxic MNI-Colin27 space as a prerequisite for subsequent meta-analysis of their functional involvement. Histological sections of 10 human post mortem brains were therefore examined. Differences in cell density were measured and used to distinguish a dorsal from a ventral part of the dentate nucleus. Probabilistic maps were calculated, which indicate the position and extent of the nuclei in 3D-space, while considering their intersubject variability. The maps of the interposed and the dentate nuclei differed with respect to their interaction patterns and functions based on meta-analytic connectivity modeling and quantitative functional decoding, respectively. For the dentate nucleus, significant (p < 0.05) co-activations were observed with thalamus, supplementary motor area (SMA), putamen, BA 44 of Broca's region, areas of superior and inferior parietal cortex, and the superior frontal gyrus (SFG). In contrast, the interposed nucleus showed more limited co-activations with SMA, area 44, putamen, and SFG. Thus, the new stereotaxic maps contribute to analyze structure and function of the cerebellum. These maps can be used for anatomically reliable and precise identification of degenerative alteration in MRI-data of patients who suffer from various cerebellar diseases.
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