ArticleRadiology and oncology2015
Thyroid lesions incidentally detected by (18)F-FDG PET-CT - a two centre retrospective study.
Article in Radiology and oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The dilemma ofEndocrine · 2021Pooled it
- Focal Thyroid Incidentalomas onFrontiers in endocrinology · 2021Pooled it
- Clinical implications of non-breast cancer related findings on FDG-PET/CT scan prior to neoadjuvant chemotherapy in patients with breast cancer.Breast cancer research and treatment · 2024Article
- PET/CT May Assist in Avoiding Pointless Thyroidectomy in Indeterminate Thyroid Nodules: A Narrative Review.Cancers · 2023Review
- Characteristics of malignant thyroid lesions on [European journal of radiology open · 2021Article
- Molecular imaging of advanced thyroid cancer: iodinated radiotracers and beyond.Medical oncology (Northwood, London, England) · 2017Review
- Malignancy rate of focal thyroid incidentaloma detected by FDG PET-CT: results of a prospective cohort study.Endocrine connections · 2017Article
- Coincidence of follicular lymphoma and hurtle cell thyroid carcinoma in a patient at presentation: which one is the source of bone metastasis? Case report and review of the literature.Clinical case reports · 2017Article
- Thyroid incidentalomas on 18FDG-PET/CT: a metabolico-pathological correlation.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2017Article
- Recurrence rate in regional lymph nodes in 737 patients with follicular or Hürthle cell neoplasms.Radiology and oncology · 2016Article
- Clinical significance of thyroid incidentalomas detected on fluorodeoxyglucose positron emission tomography scan (PETomas): An Indian experience.World journal of nuclear medicineArticle
- MANAGEMENT PRINCIPLES OF INCIDENTAL THYROID 18F-FDG UPTAKE IDENTIFIED ON 18F-FDG PET/CT IMAGING.Acta endocrinologica (Bucharest, Romania : 2005)Article
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4 authors.
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Abstract
backgroundIncidental (18)F-FDG uptake in the thyroid on PET-CT examinations represents a diagnostic challenge. The maximal standardized uptake value (SUVmax) is one possible parameter that can help in distinguishing between benign and malignant thyroid PET lesions. PATIENTS AND
methodsWe retrospectively evaluated (18)F-FDG PET-CT examinations of 5,911 patients performed at two different medical centres from 2010 to 2011. If pathologically increased activity was accidentally detected in the thyroid, the SUVmax of the thyroid lesion was calculated. Patients with incidental (18)F-FDG uptake in the thyroid were instructed to visit a thyroidologist, who performed further investigation including fine needle aspiration cytology (FNAC) if needed. Lesions deemed suspicious after FNAC were referred for surgery.
resultsIncidental (18)F-FDG uptake in the thyroid was found in 3.89% - in 230 out of 5,911 patients investigated on PET-CT. Malignant thyroid lesions (represented with focal thyroid uptake) were detected in 10 of 66 patients (in 15.2%). In the first medical centre the SUVmax of 36 benign lesions was 5.6 ± 2.8 compared to 15.8 ± 9.2 of 5 malignant lesions (p < 0.001). In the second centre the SUVmax of 20 benign lesions was 3.7 ± 2.2 compared to 5.1 ± 2.3 of 5 malignant lesions (p = 0.217). All 29 further investigated diffuse thyroid lesions were benign.
conclusionsIncidental (18)F-FDG uptake in the thyroid was found in 3.89% of patients who had a PET-CT examination. Only focal thyroid uptake represented a malignant lesion in our study - in 15.2% of all focal thyroid lesions. SUVmax should only serve as one of several parameters that alert the clinician on the possibility of thyroid malignancy.
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