Seroprevalence of equine granulocytic anaplasmosis and lyme borreliosis in Canada as determined by a point-of-care enzyme-linked immunosorbent assay (ELISA).

Gili Schvartz, Tasha Epp, Hilary J Burgess, Neil B Chilton, David L Pearl, Katharina L Lohmann

Open access · greenAbstract read

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.9field-weighted citation impact, top 30% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

Point-of-care testing in companion and food animal disease diagnostics.Frontiers in veterinary science · 2022
Review
Transfer of naturally acquired specific passive immunity against Anaplasma phagocytophilum in foals in Southeastern Pennsylvania and Northern Maryland.Journal of veterinary internal medicine
Observational

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gili SchvartzDepartment of Large Animal Clinical Sciences (Schvartz, Epp, Lohmann), Department of Veterinary Pathology (Burgess), Western College of Veterinary Medicine, and Department of Biology (Chilton), University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, Ontario N1G 2W1 (Pearl).

Tasha EppDepartment of Large Animal Clinical Sciences (Schvartz, Epp, Lohmann), Department of Veterinary Pathology (Burgess), Western College of Veterinary Medicine, and Department of Biology (Chilton), University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, Ontario N1G 2W1 (Pearl).

Hilary J BurgessDepartment of Large Animal Clinical Sciences (Schvartz, Epp, Lohmann), Department of Veterinary Pathology (Burgess), Western College of Veterinary Medicine, and Department of Biology (Chilton), University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, Ontario N1G 2W1 (Pearl).

Neil B ChiltonDepartment of Large Animal Clinical Sciences (Schvartz, Epp, Lohmann), Department of Veterinary Pathology (Burgess), Western College of Veterinary Medicine, and Department of Biology (Chilton), University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, Ontario N1G 2W1 (Pearl).

David L PearlDepartment of Large Animal Clinical Sciences (Schvartz, Epp, Lohmann), Department of Veterinary Pathology (Burgess), Western College of Veterinary Medicine, and Department of Biology (Chilton), University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, Ontario N1G 2W1 (Pearl).

Katharina L LohmannDepartment of Large Animal Clinical Sciences (Schvartz, Epp, Lohmann), Department of Veterinary Pathology (Burgess), Western College of Veterinary Medicine, and Department of Biology (Chilton), University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, Ontario N1G 2W1 (Pearl).

University of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Equine granulocytic anaplasmosis (EGA) and Lyme borreliosis (LB) are an emerging concern in Canada. We estimated the seroprevalence of EGA and equine LB by testing 376 convenience serum samples from 3 provinces using a point-of-care SNAP(®) 4Dx(®) ELISA (IDEXX Laboratories, Westbrook, Maine, USA), and investigated the agreement between the point-of-care ELISA and laboratory-based serologic tests. The estimated seroprevalence for EGA was 0.53% overall (0.49% in Saskatchewan, 0.71% in Manitoba), while the estimated seroprevalence for LB was 1.6% overall (0.49% in Saskatchewan, 2.86% in Manitoba). There was limited agreement between the point-of-care ELISA and an indirect fluorescent antibody test for EGA (kappa 0.1, PABAK 0.47) and an ELISA/Western blot combination for LB (kappa 0.23, PABAK 0.71). While the SNAP(®) 4Dx(®) ELISA yielded expected seroprevalence estimates, further evaluation of serologic tests for the purposes of disease exposure recognition may be needed.

Indexed as

Point-of-Care SystemsAnaplasmosisAnimalsCanadaEnzyme-Linked Immunosorbent AssayHorse DiseasesHorsesLyme DiseaseSensitivity and SpecificitySeroepidemiologic Studies

Identifiers

PMID26028677

PMCPMC4431153

OpenAlexW651940254

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.