ReviewEuropean respiratory review : an official journal of the European Respiratory Society2015
Diagnostic advances and opportunities in chronic thromboembolic pulmonary hypertension.
Review in European respiratory review : an official journal of the European Respiratory Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Diagnostic Performance of Magnetic Resonance Imaging in Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review.Journal of medical imaging and radiation oncology · 2026Pooled it
- A Case of Chronic Thromboembolic Pulmonary Hypertension and Pregnancy, Managed With Pulmonary Endarterectomy: Clinical Challenges, Case Report, and Literature Review.Clinical case reports · 2026Article
- Article
- The Surgical Management of Chronic Thromboembolic Pulmonary Hypertension.Journal of clinical medicine · 2025Review
- Central versus Peripheral CTEPH-Clinical and Hemodynamic Specifications.Medicina (Kaunas, Lithuania) · 2022Article
- Pulmonary vasculitis mimicking chronic thromboembolic disease.BMJ case reports · 2019Article
- Non-invasive Multimodality Cardiovascular Imaging of the Right Heart and Pulmonary Circulation in Pulmonary Hypertension.Frontiers in cardiovascular medicine · 2019Review
- Abnormal Ventilation-Perfusion Scan Is Associated with Pulmonary Hypertension in Sickle Cell Adults.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019Article
- Chronic thromboembolic pulmonary hypertension: an enigma.BMJ case reports · 2018Article
- The changing landscape of chronic thromboembolic pulmonary hypertension management.European respiratory review : an official journal of the European Respiratory Society · 2017Review
- Long-term outcomes of surgery for chronic thromboembolic pulmonary hypertension compared with medical therapy at a single Korean center.The Korean journal of internal medicine · 2017Article
- Balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension.European respiratory review : an official journal of the European Respiratory Society · 2017Review
- Clinical Study of Acute Vasoreactivity Testing in Patients with Chronic Thromboembolic Pulmonary Hypertension.Chinese medical journal · 2017Article
- An international physician survey of chronic thromboembolic pulmonary hypertension management.Pulmonary circulation · 2016Article
- A review of imaging modalities in pulmonary hypertension.Annals of thoracic medicineReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterised by the presence of thromboembolic material in the pulmonary circulation, and patients have a poor prognosis without treatment. Patients present with nonspecific symptoms, such as breathlessness and syncope, which means that other more common conditions are sometimes suspected before CTEPH, leading to delayed diagnosis and treatment. This is problematic because CTEPH is potentially curable with surgical pulmonary endarterectomy (PEA); indeed, CTEPH should always be considered in any patient with unexplained pulmonary hypertension (PH). Several key evaluations are necessary and complementary to confirm a diagnosis of CTEPH and assess operability. Echocardiography is initially used to confirm a general diagnosis of PH. Ventilation/perfusion scanning is then essential in the first stage of CTEPH diagnosis, with a wedge-shaped perfusion deficit indicative of CTEPH. This should be followed by right heart catheterisation (RHC) which is mandatory in confirming the diagnosis and providing haemodynamic parameters that are key predictors of the risk associated with PEA and subsequent prognosis. RHC is ideally coupled with conventional pulmonary angiography, the gold-standard technique for confirming the location and extent of disease, and thus whether the obstruction is surgically accessible. Computed tomographic pulmonary angiography is also now routinely used as a complementary technique to aid diagnosis and operability assessment. Recent improvements in the resolution of other noninvasive techniques, such as cardiac magnetic resonance imaging, allow for detailed reconstructions of the vascular tree and imaging of vessel defects, and interest in their use is increasing.
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