ReviewEuropean respiratory review : an official journal of the European Respiratory Society2015
Chronic thromboembolic pulmonary hypertension: a distinct disease entity.
Review in European respiratory review : an official journal of the European Respiratory Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 111 citations in OpenAlex.
- Automated CT Pulmonary Angiography-Derived Periclot Radiomics for CTEPH Detection.Pulmonary circulation · 2026Article
- Pulmonary Vascular Signaling in Pulmonary Hypertension: Potential Role of Endothelial CaArteriosclerosis, thrombosis, and vascular biology · 2026Review
- Diagnostic performance of lung perfusion SPECT/CT using perfusion defect and decrease criteria: a comparative study with CTPA in pulmonary thromboembolism.Annals of nuclear medicine · 2026Article
- The role of ventilation/perfusion scintigraphy in distinguishing acute from chronic pulmonary embolism.Emergency radiology · 2026Article
- Review
- Antiphospholipid Syndrome in Chronic Thromboembolic Pulmonary Hypertension and Chronic Thromboembolic Pulmonary Disease without Pulmonary Hypertension: Prevalence and Clinical Impact in a Dutch Cohort.TH open : companion journal to thrombosis and haemostasis · 2026Article
- Transmembrane Protein 100 Expression on Endothelial Cells Vascularizing Thrombi in Chronic Thromboembolic Pulmonary Hypertension Modulates TGFβ1-ALK1 Signaling During Angiogenesis.Pulmonary circulation · 2026Article
- Quantitative Evaluation of Lung Perfusion by Dynamic Chest Radiography in Chronic Thromboembolic Pulmonary Hypertension: Comparison With Lung Perfusion Scintigraphy.Pulmonary circulation · 2025Article
- Pulmonary hypertension aetiologies in different parts of the world.International journal of cardiology. Congenital heart disease · 2025Review
- Comparison of the value of FAPI imaging and speckle‑tracking echocardiography in assessment of right ventricular remodeling in pulmonary hypertension.BMC medical imaging · 2025Article
- Molecular Pathophysiology of Chronic Thromboembolic Pulmonary Hypertension: A Clinical Update from a Basic Research Perspective.Advances in respiratory medicine · 2024Review
- Diagnosis and Treatment Patterns of Chronic Thromboembolic Pulmonary Hypertension in Russia, Kazakhstan, Turkey, Lebanon, and Saudi Arabia: A Registry Study.Drugs - real world outcomes · 2024Article
- Portable Dynamic Chest Radiography: Literature Review and Potential Bedside Applications.Medical sciences (Basel, Switzerland) · 2024Review
- Dynamic chest radiography for pulmonary vascular diseases: clinical applications and correlation with other imaging modalities.Japanese journal of radiology · 2024Review
- Pulmonary Hypertension and the Gut Microbiome.Biomedicines · 2024Review
- Pathophysiology and Treatment of Chronic Thromboembolic Pulmonary Hypertension.International journal of molecular sciences · 2023Review
- A Case of Chronic Pulmonary Embolism Resulting in Pulmonary Hypertension and Decompensated Right Heart Failure.Cureus · 2022Article
- Central versus Peripheral CTEPH-Clinical and Hemodynamic Specifications.Medicina (Kaunas, Lithuania) · 2022Article
- Overview of Riociguat and Its Role in the Treatment of Pulmonary Hypertension.Journal of pharmacy practice · 2022Review
- EGR1 Is Implicated in Right Ventricular Cardiac Remodeling Associated with Pulmonary Hypertension.Biology · 2022Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic thromboembolic pulmonary hypertension (CTEPH) is a distinct subtype of pulmonary hypertension (PH). One disease hypothesis is that CTEPH results from the non-resolution of venous thromboembolism. CTEPH is characterised by the presence of obstructive fibrotic thromboembolic material in the major pulmonary vessels, with concomitant microvascular arteriopathy, resulting in progressive PH. The clinical presentation of CTEPH is similar to pulmonary arterial hypertension with nonspecific symptoms, but it is distinguished from pulmonary arterial hypertension by the presence of mismatched segmental defects on the ventilation/perfusion scan. The exact prevalence and incidence of CTEPH are unknown, but are thought to have been underestimated in the past. CTEPH is unique among the subgroups of PH in that it is potentially curable with pulmonary endarterectomy, a surgical intervention intended to remove the occlusive material from the pulmonary vasculature. However, in some patients the obstructions are technically inaccessible or the risk/benefit ratios are unfavourable, making the condition inoperable. It is thought that the involvement of the smaller, more distal vessels is a target for medical treatment. Untreated, CTEPH may result in right heart failure and death. The pathophysiological mechanisms which cause CTEPH are complex and have not yet been fully elucidated.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.