ArticleScientific reports2015
Incubation temperature affects the immune function of hatchling soft-shelled turtles, Pelodiscus sinensis.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 39 citations in OpenAlex.
- Diet impacts the effects of thermal stress on infection outcomes.BMC ecology and evolution · 2026Article
- Veterinary medicine in reintroduction and reinforcement of the European pond turtle Emys orbicularis: a review.BMC veterinary research · 2025Review
- Can nesting behaviour allow reptiles to adapt to climate change?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Effects of Thermal Stress on the Antioxidant Capacity, Blood Biochemistry, Intestinal Microbiota and Metabolomic Responses ofAntioxidants (Basel, Switzerland) · 2023Article
- Tissue and Temperature-Specific RNA-Seq Analysis Reveals Genomic Versatility and Adaptive Potential in Wild Sea Turtle Hatchlings (Animals : an open access journal from MDPI · 2021Article
- Heat, health and hatchlings: associations ofConservation physiology · 2020Article
- Comparative transcriptional profiling analysis of the effect of heat waves during embryo incubation on the hatchlings of the Chinese soft-shelled turtle (Ecology and evolution · 2018Article
- Supplementation with turmeric residue increased survival of the Chinese soft-shelled turtle (Pelodiscus sinensis) under high ambient temperatures.Journal of Zhejiang University. Science. BArticle
- Maternal investment and early thermal conditions affect performance and antipredator responses.Behavioral ecology : official journal of the International Society for Behavioral EcologyArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identifying how developmental temperature affects the immune system is critical for understanding how ectothermic animals defend against pathogens and their fitness in the changing world. However, reptiles have received little attention regarding this issue. We incubated eggs at three ecologically relevant temperatures to determine how incubation temperature affects the immune function of hatchling soft-shelled turtles, Pelodiscus sinensis. When exposed to bacterial infections, hatchlings from 24 °C had lower cumulative mortalities (55%, therefore, higher immunocompetence) than those from 28 °C (85%) or 32 °C (100%). Consistent with higher immunocompetence, hatchlings from low incubation temperature had higher IgM, IgD, and CD3γ expressions than their counterparts from the other two higher incubation temperatures. Conversely, the activity of immunity-related enzymes did not match the among-temperature difference in immune function. Specifically, enzyme activity was higher at intermediate temperatures (alkaline phosphatase) or was not affected by incubation temperature (acid phosphatase, lysozyme). Our study is the first to provide unequivocal evidence (at the molecular and organismal level) about the significant effect of incubation temperature on offspring immunity in reptiles. Our results also indicate that the reduced immunity induced by high developmental temperatures might increase the vulnerability of reptiles to the outbreak of diseases under global warming scenarios.
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