ReviewCurrent cardiology reports2015
Genetics of sudden cardiac death.
Review in Current cardiology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Genetics of Sudden Cardiac Arrest: Overview of Genetic Risk Factors and Aetiologies.Arrhythmia & electrophysiology review · 2025Review
- Microtubule plus-end tracking proteins: novel modulators of cardiac sodium channels and arrhythmogenesis.Cardiovascular research · 2023Article
- Identification and validation of potential hypoxia-related genes associated with coronary artery disease.Frontiers in physiology · 2023Article
- Article
- A dataset of dual calcium and voltage optical mapping in healthy and hypertrophied murine hearts.Scientific data · 2021Article
- Unique clinical features and long term follow up of survivors of sudden cardiac death in an Asian multicenter study.Scientific reports · 2021Article
- NovelFrontiers in cardiovascular medicine · 2021Article
- Risk Stratification of Sudden Cardiac Death in Patients with Heart Failure: An update.Journal of clinical medicine · 2018Review
- Competence of general practitioners in requesting and interpreting ECGs - a case vignette study.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2018Article
- Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy.Scientific reports · 2018Article
- IDENTIFYING NEW SUDDEN DEATH GENES.Transactions of the American Clinical and Climatological Association · 2018Article
- Metabolic risk factors associated with sudden cardiac death (SCD) during acute myocardial ischemia.Forensic sciences research · 2017Article
- Polymorphisms in the GNAS Gene as Predictors of Ventricular Tachyarrhythmias and Sudden Cardiac Death: Results From the DISCOVERY Trial and Oregon Sudden Unexpected Death Study.Journal of the American Heart Association · 2016Article
- Sudden cardiac death and the role of postmortem genetic testing in unexplained cases.Indian pacing and electrophysiology journalReview
- Molecular mechanisms in the pathogenesis of arrhythmogenic cardiomyopathy.Cardiovascular pathology : the official journal of the Society for Cardiovascular PathologyReview
- The link between abnormalities of calcium handling proteins and catecholaminergic polymorphic ventricular tachycardia.Tzu chi medical journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sudden cardiac death (SCD) is defined by the World Health Organization (WHO) as death within 1 h of symptom onset (witnessed) or within 24 h of being observed alive and symptom free (unwitnessed). It affects more than 3 million people annually worldwide and affects approximately 1/1000 people each year in the USA. Familial studies of syndromes with Mendelian inheritance, candidate genes analyses, and genome-wide association studies (GWAS) have helped our understanding of the genetics of SCD. We will review the genetics of arrhythmogenic hereditary syndromes with Mendelian inheritance from familial studies with structural heart disease (hypertrophic cardiomyopathy, dilated cardiomyopathy, and arrhythmogenic cardiomyopathy) as well as primary electrical causes (long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and short QT syndrome). In addition, we will review the genetics of intermediate phenotypes for SCD such as coronary artery disease and electrocardiographic variables (QT interval, QRS duration, and RR interval). Finally, we will review rare and common variants that are associated with SCD in the general population and were identified from candidate gene analyses and GWAS. Our understanding of the genetics of SCD will improve by the use of next-generation sequencing/whole-exome sequencing as well as whole-genome sequencing which have the potential to discover unsuspected common and rare genetic variants that might be associated with SCD.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.