ArticleJournal of neuro-oncology2015
Health-related quality of life in patients with high-grade gliomas: a quantitative longitudinal study.
Article in Journal of neuro-oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Physical activity and exercise in adults diagnosed with primary brain cancer: a systematic review.Journal of neuro-oncology · 2021Pooled it
- Promoting physical activity in glioma patients: Insights from Dutch healthcare professionals.Neuro-oncology practice · 2026Article
- "Such a different type of tiredness": people with brain tumour, their caregivers', and healthcare professionals' qualitative perceptions of cancer-related fatigue.Journal of cancer survivorship : research and practice · 2026Article
- Application of multidimensional cognitive training in the early postoperative period for glioma patients with cognitive impairment.Journal of neuro-oncology · 2026Article
- Self-reported physical functioning and physical fitness in glioma patients.Neuro-oncology practice · 2026Article
- Healthcare professionals' perspectives on barriers and facilitators to managing brain tumor-related personality and behavior changes.Neuro-oncology practice · 2025Article
- Unveiling the Unspoken: Exploring Taboo Thoughts and Difficult Experiences Among Carers of People With Brain Cancer.Psycho-oncology · 2025Article
- Baseline factors relating to depressive symptoms at one year postoperative in patients with diffuse glioma.Neuro-oncology practice · 2025Article
- Frequency and clinical associations of common mental disorders in adults with high-grade glioma-A multicenter study.Cancer · 2025Article
- Exploring the clinical utility of a brief screening measure of unmet supportive care needs in people with high-grade glioma.Neuro-oncology practice · 2023Article
- Patterns and predictors of anxiety and depression symptom trajectories in patients diagnosed with primary brain tumors.Journal of neuro-oncology · 2023Article
- Triaxial accelerometer-measured physical activity and functional behaviours among people with High Grade Glioma: The BrainWear Study.PloS one · 2023Article
- Determining the Research Priorities for Adult Primary Brain Tumours in Australia and New Zealand: A Delphi Study with Consumers, Health Professionals, and Researchers.Current oncology (Toronto, Ont.) · 2022Article
- Brain cancer patients' levels of distress and supportive care needs over time.Psycho-oncology · 2022Article
- Article
- Depression and Quality of Life in Patients with Gliomas: A Narrative Review.Journal of clinical medicine · 2022Review
- Anxiety and depression in patients with intracranial meningioma: a mixed methods analysis.BMC psychology · 2022Article
- Easing the Journey-an Updated Review of Palliative Care for the Patient with High-Grade Glioma.Current oncology reports · 2022Review
- Article
- Rehabilitation interventions for depression symptoms among cancer patients in Palestine: A systematic review.Frontiers in rehabilitation sciences · 2022Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnosis of a high-grade glioma usual is followed by functional impairment(s), cognitive decline and an impaired psycho-social well-being. This might well have a significant and negative impact on the health related quality of life. The purpose of this study was to explore physical activity levels, prevalence and severity of anxiety and depressive symptoms and health-related quality of life among patients with a highgrade glioma. This paper is based on a longitudinal mixed methods study. Patients (n = 30) completed questionnaires at 5 time points from time of diagnosis until the final follow-up after 1 year. Scores of Karnofsky Performance Status (KPS), physical activity, anxiety and depression and health-related quality of life (FACT-Br) are obtained. Patients' physical activity level and KPS decrease during the disease- and treatment trajectory. The majority of patients did not report any depressive symptoms, eight individuals (26.7 %) being depressed at various time points. Among a sub-group of participants who completed all study requirements for the entire study period the level of anxiety decreased significantly during the study. The FACT-Br sub-scale of emotional well-being increased significant, indicating a better HRQOL attend of followup. The diagnosis of a HGG leads to an ongoing functional decline measured as a decline of the KPS and a reduced physical activity during leisure time. Supportive care combined with rehabilitative and palliative approaches might well be valuable along the trajectory especially during the post-surgery period when anxiety is at its highest peak.
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