Evidence map›Paper›PMID 26026648›Full record

ArticleJournal of clinical monitoring and computing2016

Cardiac output method comparison studies: the relation of the precision of agreement and the precision of method.

Alexander Hapfelmeier, Maurizio Cecconi, Bernd Saugel

Abstract readComparative StudyEvaluation StudyValidation Study
PubMed Publisher
In one paragraph

Article in Journal of clinical monitoring and computing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 88 citations in OpenAlex.

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  11. Metrology part 1: definition of quality criteria.Journal of clinical monitoring and computing · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Alexander HapfelmeierInstitute of Medical Statistics and Epidemiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, Munich, Germany.
Maurizio CecconiAnaesthesia and Intensive Care, St George's Healthcare NHS Trust and St George's University of London, London, SW19 0QT, UK.
Bernd SaugelDepartment of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. bernd.saugel@gmx.de.
St George's, University of London · GBTechnical University of Munich · DEUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac output (CO) plays a crucial role in the hemodynamic management of critically ill patients treated in the intensive care unit and in surgical patients undergoing major surgery. In the field of cardiovascular dynamics, innovative techniques for CO determination are increasingly available. Therefore, the number of studies comparing these techniques with a reference, such as pulmonary artery thermodilution, is rapidly growing. There are mainly two outcomes of such method comparison studies: (1) the accuracy of agreement and (2) the precision of agreement. The precision of agreement depends on the precision of each method, i.e., the precision that the studied and the reference technique are able to achieve. We call this "precision of method". A decomposition of variance shows that method agreement does not only depend on the precision of method but also on another important source of variability, i.e., the method's general variability about the true values. Ignorance of that fact leads to falsified conclusions about the precision of method of the studied technique. In CO studies, serial measurements are frequently confused with repeated measurements. But as the actual CO of a subject changes from assessment to assessment, there is no real repetition of a measurement. This situation equals a scenario in which single measurements are given for multiple true values per subject. In such a case it is not possible to assess the precision of method.

Indexed as

AlgorithmsData Interpretation, StatisticalValidation Studies as TopicCardiac OutputHeart Function TestsReproducibility of ResultsSensitivity and SpecificityAccuracyBland–Altman analysisCardiac outputHemodynamic monitoringMethod comparisonPrecision

Identifiers

PMID26026648
OpenAlexW631380430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.