Evidence map›Paper›PMID 26026494›Full record

Trial reportDrug and alcohol dependence2015

An economic evaluation of a contingency-management intervention for stimulant use among community mental health patients with serious mental illness.

Sean M Murphy, Michael G McDonell, Sterling McPherson, Debra Srebnik, Frank Angelo, John M Roll, Richard K Ries

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. The dissemination and implementation of contingency management for substance use disorders: A systematic review.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
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  16. Psychotherapies in opioid use disorder: toward a step-care model.Journal of neural transmission (Vienna, Austria : 1996) · 2024
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  18. Methamphetamine dependence in Australia-why is 'ice' (crystal meth) so addictive?Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sean M MurphyProgram of Excellence in Addictions Research, Washington State University, Spokane, WA 99210, USA. Electronic address: sean.murphy@wsu.edu.
Michael G McDonellDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
Sterling McPhersonProgram of Excellence in Addictions Research, Washington State University, Spokane, WA 99210, USA.
Debra SrebnikKing County Mental Health, Chemical Abuse and Dependency Services Division, Seattle, WA 98104, USA.
Frank AngeloDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
John M RollProgram of Excellence in Addictions Research, Washington State University, Spokane, WA 99210, USA.
Richard K RiesDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
University of Washington · USWashington State University Spokane · USPublic Health – Seattle & King County · US

Funding

Contingency Management of Psychostimulant Abuse in the Severely Mentally IllR01DA022476 · NIDA · UNIVERSITY OF WASHINGTON · PI RIES, RICHARD K · 2007 to 2010
$1.9M
NIDA NIH HHS R01 DA022476
6 · The paper itself

Abstract

backgroundThis study examines the cost-effectiveness of contingency-management (CM) for stimulant dependence among community mental health patients with serious mental illness (SMI)

methodsEconomic evaluation of a 12-week randomized controlled trial investigating the efficacy of CM added to treatment-as-usual (CM+TAU), relative to TAU without CM, for treating stimulant dependence among patients with a SMI. The trial included 176 participants diagnosed with SMI and stimulant dependency who were receiving community mental health and addiction treatment at one community mental health center in Seattle, Washington. Participants were also assessed during a 12-week follow-up period. Positive and negative syndrome scale (PANSS) scores were used to calculate quality-adjusted life-years (QALYs) for the primary economic outcome. The primary clinical outcome, the stimulant-free year (SFY) is a weighted measure of time free from stimulants. Two perspectives were adopted, those of the provider and the payer.

resultsAt 12-weeks neither the provider ($2652, p=0.74) nor the payer ($2611, p=0.99) cost differentials were statistically significant. This was also true for the payer at 24-weeks (-$125, p=1.00). QALYs gained were similar across groups, resulting in small, insignificant differences (0.04, p=0.23 at 12-weeks; 0.01, p=0.70 at 24 weeks). CM+TAU experienced significantly more SFYs, 0.24 (p<0.001) at 12 weeks and 0.20 (p=0.002) at 24 weeks, resulting in at least an 85% chance of being considered cost-effective at a threshold of $200,000/SFY.

conclusionContingency management appears to be a wise investment for both the provider and the payer with regard to the clinical outcome of time free from stimulants.

Indexed as

Cost-Benefit AnalysisAdultBehavior TherapyCentral Nervous System StimulantsCommunity Mental Health ServicesFemaleHealth Care CostsHumansMaleMental DisordersQuality-Adjusted Life YearsSubstance-Related DisordersWashingtonCentral Nervous System StimulantsContingency managementCost effectivenessSerious mental illnessStimulant use

Identifiers

PMID26026494
PMCPMC4509830
OpenAlexW1586260281

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.