Evidence map›Paper›PMID 26025954›Full record

ArticleIranian biomedical journal2015

Molecular Genetic Analysis of the Variable Number of Tandem-Repeat Alleles at the Phenylalanine Hydroxylase Gene in Iranian Azeri Turkish Population.

Morteza Bagheri, Isa Abdi Rad, Nima Hosseini Jazani, Rasoul Zarrin, Ahad Ghazavi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian biomedical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Morteza BagheriFood and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Isa Abdi RadFood and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Nima Hosseini JazaniFood and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Rasoul ZarrinFood and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Ahad GhazaviNeurophysiology Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Urmia University · IRUrmia University of Medical Sciences

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe variable numbers of tandem-repeat (VNTR) alleles at the phenylalanine hydroxylase (PAH) gene have been used in carrier detection and prenatal diagnosis in phenylketonuria families. This study was carried out to analyze VNTR alleles at the PAH gene in Iranian Azeri Turkish population.

methodsIn this study, 200 alleles from general population were studied by PCR.

resultsThe frequencies of VNTR alleles were 45%, 46%, 2%, 3%, 1%, and 3% in studied group regarding 3, 8, 9, 11, 12, and 13 repeat copies, respectively. Statistically significant differences were not found between expected and observed frequencies of VNTR genotypes (P > 0.05).

conclusionsVNTR alleles with three and eight repeats were frequent, and the VNTR alleles with 13 repeats showed 3% frequency in the tested group. This study is the first report on tested population genetic structure using VNTR alleles at the PAH gene.

Indexed as

AllelesMinisatellite RepeatsAdultHumansIranMiddle AgedPhenylalanine HydroxylaseTurkeyYoung AdultPhenylalanine HydroxylasePhenylalanine hydroxylasePopulation geneticsVariable numbers of tandem-repeat

Identifiers

PMID26025954
PMCPMC4571015
OpenAlexW1892416065

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