Evidence map›Paper›PMID 26025592›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2015

Association between ventricular arrhythmias and myocardial mechanical dispersion assessed by strain analysis in patients with nonischemic cardiomyopathy.

Jedrzej Kosiuk, Borislav Dinov, Andreas Bollmann, Emmanuel Koutalas, Andreas Mussigbrodt, Phillipp Sommer, Arash Arya, Sergio Richter, Gerhard Hindricks, Ole A Breithardt

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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Strain Imaging and Ventricular Arrhythmia.Diagnostics (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Diagnostic value of speckle-tracking echocardiography in confirmed cardiac sarcoidosis.Clinical research in cardiology : official journal of the German Cardiac Society · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jedrzej KosiukDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany. jedrzejkosiuk@hotmail.com.
Borislav DinovDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Andreas BollmannDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Emmanuel KoutalasDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Andreas MussigbrodtDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Phillipp SommerDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Arash AryaDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Sergio RichterDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Gerhard HindricksDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Ole A BreithardtDepartment of Electrophysiology, Heart Center Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.
Leipzig Heart Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical dispersion (MD), defined as the standard deviation of time to maximum myocardial shortening assessed by 2D speckle tracking echocardiographic strain imaging (2DS), has been recently proposed as a predictor for ventricular tachycardia or fibrillation (VT/VF) in patients with ischemic cardiomyopathy and long QT syndrome. However, the role of MD in patients with non-ischemic cardiomyopathy (NICM) has not yet been studied. METHODS AND

resultsIn 20 patients with NICM (mean age 62 ± 11 years, 75 % male, mean EF 32 ± 6 %, mean QRS duration 102 ± 14 ms), we measured longitudinal strain by 2DS in a 16-segment left ventricular model and calculated the MD. Patients were divided into two groups, defined by the presence or absence of documented VT/VF. In 11 patients (55 %), VT/VF was documented. The median time from VT/VF to echocardiographic examination was 26 (IQR 15-58) months. There were no significant differences in baseline characteristics between patients with and without index events. MD was significantly greater in patients with VT/VF as compared to those without arrhythmias (84 ± 31 ms vs. 53 ± 16 ms, p = 0.017). The analysis of the ROC curve (AUC 0.81, 95 % CI 0.63-1.00, p = 0.017) revealed that dispersion >50 ms is associated with twelve times higher risk of VT/VF in patients with NICM (OR 12.5, 95 % CI 1.1-143.4, p = 0.024).

conclusionsIn this small cohort of NICM patients, greater MD was associated with a higher incidence of VT/VF.

Indexed as

AgedCardiomyopathiesEchocardiographyFemaleHumansIncidenceMaleMiddle AgedRiskTachycardia, VentricularTime FactorsVentricular FibrillationEchocardiographyMechanical dispersionSpeckle trackingVentricular arrhythmias

Identifiers

PMID26025592
OpenAlexW351855509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.