SynthesisEuropean journal of preventive cardiology2016
Association between fine particulate matter exposure and subclinical atherosclerosis: A meta-analysis.
Synthesis in European journal of preventive cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The long-term effect of exposure to respirable particulate matter on the incidence of myocardial infarction: a systematic review and meta-analysis study.Environmental science and pollution research international · 2022Pooled it
- Ambient air pollution and cardiovascular diseases: An umbrella review of systematic reviews and meta-analyses.Journal of internal medicine · 2022Pooled it
- Beyond the Usual Suspects: A Narrative Review of High-Yield Non-Traditional Risk Factors for Atherosclerosis.Journal of clinical medicine · 2026Review
- Air Pollution, Body Composition, and Vascular Age in Southern Switzerland: A Cross-Sectional Population Study.Journal of clinical medicine · 2025Article
- Air pollution and cardiovascular diseases: mechanisms, evidence, and mitigation strategies.Journal of medicine and life · 2025Review
- Particulate Matter-Induced Emerging Health Effects Associated with Oxidative Stress and Inflammation.Antioxidants (Basel, Switzerland) · 2024Review
- Increased vascular stiffness in children exposed in utero but not children exposed postnatally to emissions from a coal mine fire.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Vascular Calcification Heterogeneity from Bench to Bedside: Implications for Manifestations, Pathogenesis, and Treatment Considerations.Aging and disease · 2024Review
- Long-Term Exposure to Fine Particulate Constituents and Vascular Damage in a Population with Metabolic Abnormality in China.Journal of atherosclerosis and thrombosis · 2023Article
- Combined Associations of Physical Activity and Particulate Matter With Subsequent Cardiovascular Disease Risk Among 5-Year Cancer Survivors.Journal of the American Heart Association · 2022Article
- Impacts of Environmental Insults on Cardiovascular Aging.Current environmental health reports · 2022Review
- Household Air Pollution and Blood Pressure, Vascular Damage, and Subclinical Indicators of Cardiovascular Disease in Older Chinese Adults.American journal of hypertension · 2022Article
- Long-Term Exposure to Low-LevelEnvironmental health perspectives · 2021Article
- A Co-Twin control study of fine particulate matter and the prevalence of metabolic syndrome risk factors.Environmental research · 2021Article
- Particulate Matter-Induced Cardiovascular Dysfunction: A Mechanistic Insight.Cardiovascular toxicology · 2021Review
- Childhood traffic-related air pollution and adverse changes in subclinical atherosclerosis measures from childhood to adulthood.Environmental health : a global access science source · 2021Article
- The critical role of endothelial function in fine particulate matter-induced atherosclerosis.Particle and fibre toxicology · 2020Review
- Effects of ambient particulate matter on vascular tissue: a review.Journal of toxicology and environmental health. Part B, Critical reviews · 2020Review
- Association between Post-Diagnosis Particulate Matter Exposure among 5-Year Cancer Survivors and Cardiovascular Disease Risk in Three Metropolitan Areas from South Korea.International journal of environmental research and public health · 2020Article
- Traffic-Related Air Pollution and Carotid Plaque Burden in a Canadian City With Low-Level Ambient Pollution.Journal of the American Heart Association · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundEpidemiological studies in humans that have evaluated the association between fine particulate matter (PM2.5) and atherosclerosis have yielded mixed results.
designIn order to further investigate this relationship, we conducted a comprehensive search for studies published through May 2014 and performed a meta-analysis of all available observational studies that investigated the association between PM2.5 and three noninvasive measures of clinical and subclinical atherosclerosis: carotid intima media thickness, arterial calcification, and ankle-brachial index. METHODS AND
resultsFive reviewers selected studies based on predefined inclusion criteria. Pooled mean change estimates and 95% confidence intervals were calculated using random-effects models. Assessment of between-study heterogeneity was performed where the number of studies was adequate. Our pooled sample included 11,947 subjects for carotid intima media thickness estimates, 10,750 for arterial calcification estimates, and 6497 for ankle-brachial index estimates. Per 10 µg/m(3) increase in PM2.5 exposure, carotid intima media thickness increased by 22.52 µm but this did not reach statistical significance (p = 0.06). We did not find similar associations for arterial calcification (p = 0.44) or ankle-brachial index (p = 0.85).
conclusionOur meta-analysis supports a relationship between PM2.5 and subclinical atherosclerosis measured by carotid intima media thickness. We did not find a similar relationship between PM2.5 and arterial calcification or ankle-brachial index, although the number of studies was small.
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Registered trials
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