ArticleJournal of microbiology (Seoul, Korea)2015
An endophytic Coniochaeta velutina producing broad spectrum antimycotics.
Article in Journal of microbiology (Seoul, Korea), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Isolation, identification and biocontrol potential evaluation of bacterial strain HZ-61 against tomato gray mold.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Article
- Age-dependent variations in leaf-endophytic microbiota and biocontrol potential in Camellia oleifera.Scientific reports · 2025Article
- A Comparison of Rice Root Microbial Dynamics in Organic and Conventional Paddy Fields.Microorganisms · 2024Article
- Filamentous Fungi Associated with Disease Symptoms in Non-Native Giant Sequoia (Pathogens (Basel, Switzerland) · 2024Article
- Analysis of endophytic bacterial flora of mulberry cultivars susceptible and resistant to bacterial wilt using metagenomic sequencing and culture-dependent approach.World journal of microbiology & biotechnology · 2023Article
- Access to Anti-Biofilm Compounds from Endolichenic Fungi Using a Bioguided Networking Screening.Journal of fungi (Basel, Switzerland) · 2022Article
- Endophytes, a Potential Source of Bioactive Compounds to Curtail the Formation-Accumulation of Advanced Glycation End Products: A Review.Molecules (Basel, Switzerland) · 2022Review
- Seasonal Characterization of the Endophytic Fungal Microbiome of Mulberry (Microorganisms · 2021Article
- We and herbivores eat endophytes.Microbial biotechnology · 2021Review
- Fungal Planet description sheets: 1182-1283.Persoonia · 2021Article
- Genome expansion by allopolyploidization in the fungal strainBiotechnology for biofuels · 2019Article
- Two new cellulolytic fungal species isolated from a 19Scientific reports · 2018Article
- Fungal Endophyte-Mediated Antibiotic and Antixenotic Plant Resistance to Herbivorous Insects.Physiologia plantarumReview
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An endophyte (PC27-5) was isolated from stem tissue of Western hemlock (Tsuga heterophylla) in a Pacific Northwest temperate rainforest. Phylogenetic analyses, based on ITS-5.8S rDNA and 18S rDNA sequence data, combined with cultural and morphological analysis showed that endophyte PC27-5 exhibited all characteristics of a fungus identical to Coniochaeta velutina. Furthermore, wide spectrum antimycotics were produced by this endophyte that were active against such plant pathogens as Sclerotinia sclerotiorum, Pythium ultimum, and Verticillium dahliae and lethal to Phythophthora cinnamomi, Pythium ultimum, and Phytophthora palmivora in plate tests. The bioactive components were purified through organic solvent extraction, followed by silica column chromatography, and finally preparative HPLC. The minimum inhibitory concentration of the active fraction to Pythium ultimum, which was gained from preparative HPLC, was 11 μg/ml. UPLC-HRMS analysis showed there were two similar components in the antimycotic fraction. Their molecular formulae were established as C30H22O11 (compound I) and C30H22O10 (compound II) respectively, and preliminary spectral results indicate that they are anthroquinone glycosides. Other non-biologically active compounds were identified in culture fluids of this fungus by spectral means as emodin and chrysophanol--anthroquinone derivatives. This is the first report that Coniochaeta velutina as an endophyte produces bioactive antifungal components.
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