Evidence map›Paper›PMID 26025063›Full record

ArticleInternational urology and nephrology2015

Risk factors for severe hypocalcemia after parathyroidectomy in prevalent dialysis patients with secondary hyperparathyroidism.

Wan-Chuan Tsai, Yu-Sen Peng, Yen-Ling Chiu, Hon-Yen Wu, Mei-Fen Pai, Shih-Ping Hsu, Ju-Yeh Yang, Kuei-Ting Tung, Hung-Yuan Chen

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Article in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Construction and validation of a risk prediction model for early hungry bone syndrome in maintenance hemodialysis patients post-parathyroidectomy.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
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  15. Use ofQuantitative imaging in medicine and surgery · 2021
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wan-Chuan TsaiDivision of Nephrology, Department of Internal Medicine, Far Eastern Memorial Hospital, No. 21, Section 2, Nanya South Road, Banqiao District, New Taipei City, 220, Taiwan, Republic of China.
Yu-Sen Peng
Yen-Ling Chiu
Hon-Yen Wu
Mei-Fen Pai
Shih-Ping Hsu
Ju-Yeh Yang
Kuei-Ting Tung
Hung-Yuan Chen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHypocalcemia is one of the common complications after parathyroidectomy (PTX). Severe hypocalcemia (SH) can lead to tetany, cardiac arrhythmia and even sudden death. However, predictors for the development of SH in patients with secondary hyperparathyroidism demonstrated in some small-scale studies with a limited sample size remain inconclusive.

methodsA retrospective chart review of 420 consecutive dialysis patients who underwent PTX during a 12-year period was performed. We checked serum levels of calcium (Ca), phosphorus (P), alkaline phosphatase (ALP) and intact parathyroid hormone (iPTH) for three consecutive days postoperatively. SH was defined as the minimum values of serum calcium lower than 1.875 mmol/L (7.5 mg/dL) within 3 days after operation.

resultsThe mean (±SD) age of our study population was 53 ± 12 years, and more than half (57 %) were female. SH occurred in 37 % of the patients after PTX. Using a multivariate stepwise logistic regression analysis, lower preoperative levels of Ca (odds ratio 0.69, 95 % CI 0.60-0.79, P < 0.001), higher preoperative levels of iPTH (odds ratio 1.04, 95 % CI 1.00-1.07, P = 0.048), P (odds ratio 2.43, 95 % CI 1.49-3.95, P < 0.001) and ALP (odds ratio 1.08, 95 % CI 1.05-1.11, P < 0.001) were found to be independent predictors of occurrence of SH following PTX.

conclusionsThe readily obtainable preoperative laboratory parameters including Ca, iPTH, P, and ALP will allow identification of a subgroup of patients who are at greater risk for the development of SH following PTX.

Indexed as

Hyperparathyroidism, SecondaryHypocalcemiaRenal Insufficiency, ChronicAdultAlkaline PhosphataseBiomarkersCalciumFemaleHumansMaleMiddle AgedParathyroidectomyParathyroid HormonePhosphorusPredictive Value of TestsPreoperative PeriodAlkaline PhosphataseBiomarkersCalciumParathyroid HormonePhosphorus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.