ArticlePlant physiology2015
The WRKY45-Dependent Signaling Pathway Is Required For Resistance against Striga hermonthica Parasitism.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 62 citations in OpenAlex.
- Maize phenylalanine ammonia-lyase produces (R)-β-tyrosine, a growth inhibitor for the parasitic weed Striga hermonthica.The Plant journal : for cell and molecular biology · 2026Article
- Article
- Resolving intergenotypic Striga resistance in sorghum.Journal of experimental botany · 2023Article
- Effects of LPS fromMicroorganisms · 2023Article
- Growth-defence trade-off in rice: fast-growing and acquisitive genotypes have lower expression of genes involved in immunity.Journal of experimental botany · 2023Article
- Maize Lethal Necrosis disease: review of molecular and genetic resistance mechanisms, socio-economic impacts, and mitigation strategies in sub-Saharan Africa.BMC plant biology · 2022Review
- Heinz-resistant tomato cultivars exhibit a lignin-based resistance to field dodder (Cuscuta campestris) parasitism.Plant physiology · 2022Article
- Association mapping for broomrape resistance in sunflower.Frontiers in plant science · 2022Article
- Association analysis for resistance to Striga hermonthica in diverse tropical maize inbred lines.Scientific reports · 2021Article
- GWAS provides biological insights into mechanisms of the parasitic plant (Striga) resistance in sorghum.BMC plant biology · 2021Article
- Current progress in Striga management.Plant physiology · 2021Article
- Mechanisms of resistance and virulence in parasitic plant-host interactions.Plant physiology · 2021Article
- Identification of QTLs for grain yield and other traits in tropical maize under Striga infestation.PloS one · 2020Article
- Identification of main-effect quantitative trait loci (QTLs) for low-temperature stress tolerance germination- and early seedling vigor-related traits in rice (Molecular breeding : new strategies in plant improvement · 2020Article
- Jasmonates-the Master Regulator of Rice Development, Adaptation and Defense.Plants (Basel, Switzerland) · 2019Review
- The Structural Integrity of Lignin Is Crucial for Resistance againstPlant physiology · 2019Article
- Genome-Wide Expression Profiling ofFrontiers in plant science · 2017Article
- Molecular Parasitic Plant-Host Interactions.PLoS pathogens · 2016Review
- The Transcription Factor OsWRKY45 Negatively Modulates the Resistance of Rice to the Brown Planthopper Nilaparvata lugens.International journal of molecular sciences · 2016Article
- Genus-Wide Comparative Genome Analyses of Colletotrichum Species Reveal Specific Gene Family Losses and Gains during Adaptation to Specific Infection Lifestyles.Genome biology and evolution · 2016Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The root hemiparasite witchweed (Striga spp.) is a devastating agricultural pest that causes losses of up to $1 billion US annually in sub-Saharan Africa. Development of resistant crops is one of the cost-effective ways to address this problem. However, the molecular mechanisms underlying resistance are not well understood. To understand molecular events upon Striga spp. infection, we conducted genome-scale RNA sequencing expression analysis using Striga hermonthica-infected rice (Oryza sativa) roots. We found that transcripts grouped under the Gene Ontology term defense response were significantly enriched in up-regulated differentially expressed genes. In particular, we found that both jasmonic acid (JA) and salicylic acid (SA) pathways were induced, but the induction of the JA pathway preceded that of the SA pathway. Foliar application of JA resulted in higher resistance. The hebiba mutant plants, which lack the JA biosynthesis gene allene oxide cyclase, exhibited severe S. hermonthica susceptibility. The resistant phenotype was recovered by application of JA. By contrast, the SA-deficient NahG rice plants were resistant against S. hermonthica, indicating that endogenous SA is not required for resistance. However, knocking down WRKY45, a regulator of the SA/benzothiadiazole pathway, resulted in enhanced susceptibility. Interestingly, NahG plants induced the JA pathway, which was down-regulated in WRKY45-knockdown plants, linking the resistant and susceptible phenotypes to the JA pathway. Consistently, the susceptibility phenotype in the WRKY45-knockdown plants was recovered by foliar JA application. These results point to a model in which WRKY45 modulates a cross talk in resistance against S. hermonthica by positively regulating both SA/benzothiadiazole and JA pathways.
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