ReviewEndocrine2016
Particulate matter pollutants and risk of type 2 diabetes: a time for concern?
Review in Endocrine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Exposure to particulate matters and risk of diabetes-related mortality: a systematic review and meta-analysis.Environmental health and preventive medicine · 2026Pooled it
- Associations of Exposure to Air Pollution with Insulin Resistance: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2018Pooled it
- Occupational particle exposure and diabetes: a cohort study in Swedish construction workers.International archives of occupational and environmental health · 2026Article
- Effect of particulate matter (PMPakistan journal of medical sciences · 2025Article
- Type 2 diabetes attributable to ambient particulate matter pollution: a global burden study from 1990 to 2019.Frontiers in public health · 2024Article
- The Association Between PM2.5 Exposure and Diabetes Mellitus Among Thai Army Personnel.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice.Particle and fibre toxicology · 2023Article
- Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice.Particle and fibre toxicology · 2023Article
- Acute exposure to air pollutants increase the risk of acute glaucoma.BMC public health · 2022Article
- Oxidative Stress Biomarkers in the Relationship between Type 2 Diabetes and Air Pollution.Antioxidants (Basel, Switzerland) · 2021Review
- Alternatives to Insulin for the Regulation of Blood Sugar Levels in Type 2 Diabetes.International journal of molecular sciences · 2020Review
- Exposure to urban particulate matter and its association with human health risks.Environmental science and pollution research international · 2020Review
- IRF4 and STAT3 activities are associated with the imbalanced differentiation of T-cells in responses to inhalable particulate matters.Respiratory research · 2020Article
- Traffic-Related Air Pollution and Carotid Plaque Burden in a Canadian City With Low-Level Ambient Pollution.Journal of the American Heart Association · 2020Article
- Age-Period-Cohort Analysis of Type 2 Diabetes Mortality Attributable to Particulate Matter Pollution in China and the U.S.Journal of diabetes research · 2020Article
- Association of Urinary Polycyclic Aromatic Hydrocarbons and Diabetes in Korean Adults: Data from the Korean National Environmental Health Survey Cycle 2 (2012-2014).Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Association of Prenatal and Perinatal Exposures to Particulate Matter With Changes in Hemoglobin A1c Levels in Children Aged 4 to 6 Years.JAMA network open · 2019Observational
- Air pollution-associated changes in biomarkers of diabetes risk.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
- Metabolomics analysis of a mouse model for chronic exposure to ambient PMEnvironmental pollution (Barking, Essex : 1987) · 2019Article
- Early life stress, air pollution, inflammation, and disease: An integrative review and immunologic model of social-environmental adversity and lifespan health.Neuroscience and biobehavioral reviews · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The World Health Organization estimates that worldwide in 2012 around 7 million deaths occurred prematurely due to air pollution, which is now the world's largest single environmental health risk. The higher premature mortality associated with air pollution is due to exposure to small particulate matter of 10 microns (PM10) or less in diameter. Exposure to air pollution has also been suggested as a contributing to diabetes incidence and progression. There are a number of possible biological pathways linking air pollutants to diabetes, including endothelial dysfunction, dysregulation of the visceral adipose tissue through inflammation, hepatic insulin resistance, elevated hemoglobin A1c level, elevated blood pressure, and alterations in autonomic tone, which may increase insulin resistance. The risk of future diabetes associated with exposure to 10 μg/m(3) increase of PM2.5 has been quantified in the range of 10 to 27%; the risk of diabetes mortality associated with PM2.5 appears to be quite lower, around 1% for each increment exposure of 10 μg/m(3) of both PM2.5 and PM10. Limitations of the current epidemiological evidence include the complex mixture of pollutants, the different design of the studies, the limited data available for non Western populations, and the lack of demonstration that improvement of air quality is associated with a decrease incidence of type 2 diabetes. Although the most sources of outdoor air pollution are well beyond the control of individuals, people should be informed that there are means to reduce the burden of air pollutants on diabetes risk, including avoidance of passive smoking, adoption of an healthy diet, and increasing leisure-time physical activity.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.