ArticleEuropean radiology2016
Assessment of CF lung disease using motion corrected PROPELLER MRI: a comparison with CT.
Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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35 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- State-of-the-art review of lung imaging in cystic fibrosis with recommendations for pulmonologists and radiologists from the "iMAging managEment of cySTic fibROsis" (MAESTRO) consortium.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- A preliminary evaluation of chest magnetic resonance imaging in adult patients with non-cystic fibrosis bronchiectasis.La Radiologia medica · 2026Article
- Contemporary 0.55 T MRI for Lung Disease Assessment in Children and Young Adults with Cystic Fibrosis: A Proof-of-Concept Study.Tomography (Ann Arbor, Mich.) · 2026Article
- Assessing the feasibility of neonatal chest MRI for bronchopulmonary dysplasia using a standard 1.5-Tesla scanner.European radiology · 2026Article
- Enhanced image quality in head and neck MRI with PROPELLER and deep learning reconstruction.European journal of radiology open · 2026Article
- Pulmonary MRI in Newborns and Children.Journal of magnetic resonance imaging : JMRI · 2025Review
- MDCT and MRI in Bronchiectasis in Older Children and Young Adults - A Non-Inferiority Trial.Indian journal of pediatrics · 2025Article
- Automated scoring of airway abnormalities and mucus plugging in chest magnetic resonance imaging of cystic fibrosis using artificial intelligence.Computational and structural biotechnology journal · 2025Article
- Thoracic magnetic resonance imaging in non-tuberculous mycobacterial pulmonary disease: Characteristics and potential implementation.PloS one · 2025Article
- Acute Respiratory Failure in Children: A Clinical Update on Diagnosis.Children (Basel, Switzerland) · 2024Review
- Automated lung segmentation on chest MRI in children with cystic fibrosis.Frontiers in medicine · 2024Article
- Comparison of deep learning-based reconstruction of PROPELLER Shoulder MRI with conventional reconstruction.Skeletal radiology · 2023Article
- MR imaging of the airways.The British journal of radiology · 2023Review
- Application of deep learning-based image reconstruction in MR imaging of the shoulder joint to improve image quality and reduce scan time.European radiology · 2023Article
- Strain Identification and Drug Resistance Analysis of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in Nontuberculous Mycobacterial Lung Disease.Infection and drug resistance · 2023Article
- Lung and large airway imaging: magnetic resonance imaging versus computed tomography.Pediatric radiology · 2022Review
- Management of respiratory tract exacerbations in people with cystic fibrosis: Focus on imaging.Frontiers in pediatrics · 2022Review
- Cross-sectional analysis of follow-up chest MRI and chest CT scans in patients previously affected by COVID-19.La Radiologia medica · 2021Article
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Authors and funding
12 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo date, PROPELLER MRI, a breathing-motion-insensitive technique, has not been assessed for cystic fibrosis (CF) lung disease. We compared this technique to CT for assessing CF lung disease in children and adults.
methodsThirty-eight stable CF patients (median 21 years, range 6-51 years, 22 female) underwent MRI and CT on the same day. Study protocol included respiratory-triggered PROPELLER MRI and volumetric CT end-inspiratory and -expiratory acquisitions. Two observers scored the images using the CF-MRI and CF-CT systems. Scores were compared with intra-class correlation coefficient (ICC) and Bland-Altman plots. The sensitivity and specificity of MRI versus CT were calculated.
resultsMRI sensitivity for detecting severe CF bronchiectasis was 0.33 (CI 0.09-0.57), while specificity was 100% (CI 0.88-1). ICCs for bronchiectasis and trapped air were as follows: MRI-bronchiectasis (0.79); CT-bronchiectasis (0.85); MRI-trapped air (0.51); CT-trapped air (0.87). Bland-Altman plots showed an MRI tendency to overestimate the severity of bronchiectasis in mild CF disease and underestimate bronchiectasis in severe disease.
conclusionsMotion correction in PROPELLER MRI does not improve assessment of CF lung disease compared to CT. However, the good inter- and intra-observer agreement and the high specificity suggest that MRI might play a role in the short-term follow-up of CF lung disease (i.e. pulmonary exacerbations). KEY POINTS: PROPELLER MRI does not match CT sensitivity to assess CF lung disease. PROPELLER MRI has lower sensitivity than CT to detect severe bronchiectasis. PROPELLER MRI has good to very good intra- and inter-observer variability. PROPELLER MRI can be used for short-term follow-up studies in CF.
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