Evidence map›Paper›PMID 26024495›Full record

ReviewNutrition reviews2015

Taste perception, associated hormonal modulation, and nutrient intake.

Hillary B Loper, Michael La Sala, Cedrick Dotson, Nanette Steinle

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Nutrition reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05528874 (Glycemic Index Analysis of Functional Bakery Products on a Group of Healthy Volunteers, a NUTRACORE Study), which is not on this map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05528874 nacompletednot on this mapstarted 2022, after this paper: background citation

Glycemic Index Analysis of Functional Bakery Products on a Group of Healthy Volunteers, a NUTRACORE Study

TypeinterventionalSponsorAzienda Ospedaliero Universitaria Maggiore della CaritaRan2022 to 2023Enrolled13ConditionsHyperglycemia, Hyperglycemia, Postprandial, Appetitive Behavior, HyperinsulinismArmsSame intervention for both groups: glycaemic index assessment of 3 biscuits recipes, Crossover: Recipe 4 before recipe 5, Crossover: Recipe 5 before recipe 4
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 131 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Changes in taste and odor sensitivities during repeated bicycle ergometer exercises.Journal of the International Society of Sports Nutrition · 2025
    Article
  5. Article
  6. Variations in basic taste perception and body mass index.Journal of diabetes and metabolic disorders · 2025
    Article
  7. Fat taste responsiveness, but not dietary fat intake, is affected inbioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hillary B LoperH.B. Loper is with the Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. M. La Sala and C. Dotson are with the Division of Addiction Medicine, Center for Smell and Taste, Department of Neuroscience and Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA. N Steinle is with the Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore, MD, USA.
Michael La SalaH.B. Loper is with the Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. M. La Sala and C. Dotson are with the Division of Addiction Medicine, Center for Smell and Taste, Department of Neuroscience and Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA. N Steinle is with the Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore, MD, USA.
Cedrick DotsonH.B. Loper is with the Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. M. La Sala and C. Dotson are with the Division of Addiction Medicine, Center for Smell and Taste, Department of Neuroscience and Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA. N Steinle is with the Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore, MD, USA.
Nanette SteinleH.B. Loper is with the Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. M. La Sala and C. Dotson are with the Division of Addiction Medicine, Center for Smell and Taste, Department of Neuroscience and Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA. N Steinle is with the Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore, MD, USA nsteinle@medicine.umaryland.edu.
Florida College · USUniversity of Florida · USUniversity of Maryland, Baltimore · US

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Modulation of Taste-Related Behavior by Molecular Mediators of Appetite & SatietyR01DC012819 · NIDCD · UNIVERSITY OF FLORIDA · PI MUNGER, STEVEN D · 2013 to 2017
$1.8M
NIDCD NIH HHS R01 DC012819NIDDK NIH HHS P30 DK072488
6 · The paper itself

Abstract

It is well known that taste perception influences food intake. After ingestion, gustatory receptors relay sensory signals to the brain, which segregates, evaluates, and distinguishes the stimuli, leading to the experience known as "flavor." It is well accepted that five taste qualities – sweet, salty, bitter, sour, and umami – can be perceived by animals. In this review, the anatomy and physiology of human taste buds, the hormonal modulation of taste function, the importance of genetic chemosensory variation, and the influence of gustatory functioning on macronutrient selection and eating behavior are discussed. Individual genotypic variation results in specific phenotypes of food preference and nutrient intake. Understanding the role of taste in food selection and ingestive behavior is important for expanding our understanding of the factors involved in body weight maintenance and the risk of chronic diseases including obesity, atherosclerosis, cancer, diabetes, liver disease, and hypertension.

Indexed as

Choice BehaviorEnergy IntakeFeeding BehaviorFood PreferencesGenetic VariationHumansTasteTaste BudsTaste Perceptionchemosensationgustatory systemtaste perception

Identifiers

PMID26024495
PMCPMC4555787
OpenAlexW1993464077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.