ArticleInvestigative ophthalmology & visual science2015
Eye growth in term- and preterm-born eyes modeled from magnetic resonance images.
Article in Investigative ophthalmology & visual science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Association of retinopathy of prematurity with early refractive development in mid-preterm infants.Eye (London, England) · 2026Article
- Refractive Status and Biometric Characteristics of Children With Familial Exudative Vitreoretinopathy.Investigative ophthalmology & visual science · 2023Article
- Corneal topography in preterm children aged 2 years to 12 years with or without retinopathy of prematurity.Eye (London, England) · 2023Article
- The Development of Retinal Function and Refractive Error in Children With Retinopathy of Prematurity.Investigative ophthalmology & visual science · 2023Article
- Modelling eye lengths and refractions in the periphery.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023Article
- Longitudinal Change of Refractive Error in Retinopathy of Prematurity Treated With Intravitreal Bevacizumab or Laser Photocoagulation.American journal of ophthalmology · 2022Article
- Article
- The Existence and Regression of Persistent Bergmeister's Papilla in Myopic Children Are Associated With Axial Length.Translational vision science & technology · 2021Article
- Anterior Chamber Measurements in Healthy Children: A Cross-Sectional Study Using Optical Coherence Tomography.Translational vision science & technology · 2021Article
- The Fovea in Retinopathy of Prematurity.Investigative ophthalmology & visual science · 2020Article
- Ocular Component Development during Infancy and Early Childhood.Optometry and vision science : official publication of the American Academy of Optometry · 2018Article
- The neural retina in retinopathy of prematurity.Progress in retinal and eye research · 2017Review
- Extrafoveal Cone Packing in Eyes With a History of Retinopathy of Prematurity.Investigative ophthalmology & visual science · 2016Article
- Retinal, visual, and refractive development in retinopathy of prematurity.Eye and brain · 2016Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeWe generated a model of eye growth and tested it against an eye known to develop abnormally, one with a history of retinopathy of prematurity (ROP).
methodsWe reviewed extant magnetic resonance images (MRIs) from term and preterm-born patients for suitable images (n = 129). We binned subjects for analysis based upon postmenstrual age at birth (in weeks) and ROP history ("Term" ≥ 37, "Premature" ≤ 32 with no ROP, "ROP" ≤ 32 with ROP). We measured the axial positions and curvatures of the cornea, anterior and posterior lens, and inner retinal surface. We fit anterior chamber depth (ACD), posterior segment depth (PSD), axial length (AL), and corneal and lenticular curvatures with logistic growth curves that we then evaluated for significant differences. We also measured the length of rays from the centroid to the surface of the eye at 5° intervals, and described the length versus age relationship of each ray, L(ray)(x), using the same logistic growth curve. We determined the rate of ray elongation, E(ray)(x), from L(ray)dy/dx. Then, we estimated the scleral growth that accounted for E(ray)(x), G(x), at every age and position.
resultsRelative to Term, development of ACD, PSD, AL, and corneal and lenticular curvatures was delayed in ROP eyes, but not Premature eyes. In Term infants, G(x) was fast and predominantly equatorial; in age-matched ROP eyes, maximal G(x) was offset by approximately 90°.
conclusionsWe produced a model of normal eye growth in term-born subjects. Relative to normal, the ROP eye is characterized by delayed, abnormal growth.
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