Evidence map›Paper›PMID 26023327›Full record

ArticleChemical science2015

Ruthenium-Caged Antisense Morpholinos for Regulating Gene Expression in Zebrafish Embryos.

J C Griepenburg, T L Rapp, P J Carroll, J Eberwine, I J Dmochowski

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Bicyclic Caged Morpholino Oligonucleotides for Optical Gene Silencing.Chembiochem : a European journal of chemical biology · 2022
    Article
  8. Review
  9. Article
  10. Review
  11. Conditionally Activated ("Caged") Oligonucleotides.Molecules (Basel, Switzerland) · 2021
    Review
  12. Caspase-Activated Oligonucleotide Probe.Bioconjugate chemistry · 2020
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Optochemical Control of Biological Processes in Cells and Animals.Angewandte Chemie (International ed. in English) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

J C GriepenburgDepartment of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104, United States.
T L RappDepartment of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104, United States.
P J CarrollDepartment of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104, United States.
J EberwineDepartment of Pharmacology, Perelman School of Medicine, University of Pennsylvania, 37 John Morgan Building, 3620 Hamilton Walk, Philadelphia, Pennsylvania 19104, United States.
I J DmochowskiDepartment of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104, United States.
California University of Pennsylvania · USUniversity of Pennsylvania · USPhiladelphia University · US

Funding

Oligonucleotides for turning genes on and off with lightR01GM083030 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DMOCHOWSKI, IVAN JULIAN · 2008 to 2017
$3.0M
LEICA TCS SP2 AOBS UV CONFOCAL SYSTEM: EMBRYO DEVELOPMENTS10RR021113 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI DMOCHOWSKI, IVAN JULIAN · 2005 to 2005
$497k
Time-Of-Flight Instrument with Variable Ionization SourcesS10RR023444 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI DMOCHOWSKI, IVAN JULIAN · 2007 to 2007
$308k
NCRR NIH HHS S10 RR021113NCRR NIH HHS S10 RR023444NIGMS NIH HHS R01 GM083030
6 · The paper itself

Abstract

Photochemical approaches afford high spatiotemporal control over molecular structure and function, for broad applications in materials and biological science. Here, we present the first example of a visible light responsive ruthenium-based photolinker, Ru(bipyridine)

Identifiers

PMID26023327
PMCPMC4443914
OpenAlexW2150631626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.