ArticleKorean circulation journal2015
The Association between Subclinical Hypothyroidism and Epicardial Adipose Tissue Thickness.
Article in Korean circulation journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Non-invasive markers of cardiovascular risk in patients with subclinical hypothyroidism: A systematic review and meta-analysis of 27 case control studies.Scientific reports · 2018Pooled it
- Association of Hypothyroidism With Atrial Substrate Burden and Recurrence Following Catheter Ablation of Atrial Fibrillation.Korean circulation journal · 2026Article
- Hidden Remodeling in Hypothyroidism: Insights From AF Ablation.Korean circulation journal · 2026Article
- Association between Neck Circumference and Thyroid Disease: Findings of a Nationwide Cross-Sectional Study in Korea.Iranian journal of public health · 2024Article
- Subclinical Hypothyroidism Represents Visceral Adipose Indices, Especially in Women With Cardiovascular Risk.Journal of the Endocrine Society · 2021Article
- No Association between Neck Circumference and Free Triiodothyronine in Euthyroid Men.International journal of endocrinology · 2021Article
- Cardiovascular Risk Assessment in Subclinical Hypothyroid Individuals with Thyroid-stimulating Hormone <10 uIU/ml.Indian journal of endocrinology and metabolismArticle
- Utility of Epicardial Fat Thickness in Subclinical Hypothyroid Children to Determine Existence of Subclinical Atherosclerosis in Them.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesSubclinical hypothyroidism (SH) is considered to be a potential risk factor for cardiovascular disease. Epicardial adipose tissue (EAT) thickness is also closely related to cardiovascular disorders. The aim of this study was to evaluate whether SH is associated with higher EAT thickness. SUBJECTS AND
methodsFifty-one consecutive patients with SH and 51 healthy control subjects were prospectively enrolled into this trial. Thyroid hormone levels, lipid parameters, body mass index, waist and neck circumference, and EAT thickness measured by echocardiography were recorded in all subjects.
resultsMean EAT thickness was increased in the SH group compared to the control group (6.7±1.4 mm vs. 4.7±1.2 mm, p<0.001). EAT thickness was shown to be correlated with thyroid stimulating hormone level (r=0.303, p=0.002). Multivariate logistic regression analysis revealed that EAT thickness was independently associated with SH {odds ratio (OR): 3.87, 95% confidence interval (CI): 1.92-7.78, p<0.001; OR: 3.80, 95% CI: 2.18-6.62, p<0.001}.
conclusionEpicardial adipose tissue thickness is increased in patients with SH compared to control subjects, and this increase in EAT thickness may be associated with the potential cardiovascular adverse effects of SH.
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