Evidence map›Paper›PMID 26023288›Full record

ArticleInternational journal of mass spectrometry2014

Intrinsic Size Parameters for Palmitoylated and Carboxyamidomethylated Peptides.

Zhiyu Li, Jonathan M Dilger, Vikas Pejaver, David Smiley, Randy J Arnold, Sean D Mooney, Suchetana Mukhopadhyay, Predrag Radivojac, David E Clemmer

Abstract read
In one paragraph

Article in International journal of mass spectrometry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiyu LiDepartment of Chemistry, Indiana University, Bloomington, IN 47405.
Jonathan M DilgerDepartment of Chemistry, Indiana University, Bloomington, IN 47405.
Vikas PejaverDepartment of Computer Science and Informatics, Indiana University, Bloomington, IN 47405.
David SmileyDepartment of Chemistry, Indiana University, Bloomington, IN 47405.
Randy J ArnoldDepartment of Chemistry, Indiana University, Bloomington, IN 47405.
Sean D MooneyBuck Institute for Research on Aging, Novato, CA 94945.
Suchetana MukhopadhyayDepartment of Biology, Indiana University, Bloomington, IN 47405.
Predrag RadivojacDepartment of Computer Science and Informatics, Indiana University, Bloomington, IN 47405.
David E ClemmerDepartment of Chemistry, Indiana University, Bloomington, IN 47405.

Funding

Informatic Profiling of Clinically Relevant MutationR01LM009722 · NLM · UNIVERSITY OF WASHINGTON · PI MOONEY, SEAN DAVID · 2007 to 2014
$3.5M
Computational approaches to protein identification and quantification using MS/MSR01GM103725 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI RADIVOJAC, PREDRAG · 2012 to 2015
$1.7M
NIGMS NIH HHS R01 GM103725NLM NIH HHS R01 LM009722
6 · The paper itself

Abstract

Cross sections for 61 palmitoylated peptides and 73 cysteine-unmodified peptides are determined and used together with a previously obtained tryptic peptide library to derive a set of intrinsic size parameters (ISPs) for the palmitoyl (Pal) group (1.26 ± 0.04), carboxyamidomethyl (Am) group (0.92 ± 0.04), and the 20 amino acid residues to assess the influence of Pal- and Am-modification on cysteine and other amino acid residues. These values highlight the influence of the intrinsic hydrophobic and hydrophilic nature of these modifications on the overall cross sections. As a part of this analysis, we find that ISPs derived from a database of a modifier on one amino acid residue (Cys

Identifiers

PMID26023288
PMCPMC4443490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.