ArticleJournal of toxicologic pathology2015
Autopsy report for a caffeine intoxication case and review of the current literature.
Article in Journal of toxicologic pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Pooled it
- Pooled it
- Non-oliguric acute renal failure secondary to a potentially lethal dose of caffeine with acute intoxication: a case report.BMC nephrology · 2024Article
- What is more common in fatal caffeine intoxication - suicide or unintentional overdose?Arhiv za higijenu rada i toksikologiju · 2024Review
- Estimate the prevalence of daily caffeine consumption, caffeine use disorder, caffeine withdrawal and perceived harm in Iran: a cross-sectional study.Scientific reports · 2024Article
- Molecular autopsy for sudden death in Japan.Journal of toxicologic pathology · 2024Review
- Treatment of Lethal Caffeine Overdose with Haemodialysis: A Case Report and Review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2022Article
- Central Nervous System Stimulants Limit Caffeine Transport at the Blood-Cerebrospinal Fluid Barrier.International journal of molecular sciences · 2022Article
- A case of refractory ventricular fibrillation after caffeine poisoning successfully treated by supportive care.Toxicology reports · 2022Article
- Caffeine Intoxication: Unregulated, Over-the-Counter Sale of Potentially Deadly Supplements.Cureus · 2022Article
- Article
- Massive β1-Adrenergic Receptor Reaction Explains Irreversible Acute Arrhythmia in a Fatal Case of Acute Pure Caffeine Intoxication.Cardiovascular toxicology · 2021Article
- Occurrence, fate, persistence and remediation of caffeine: a review.Environmental science and pollution research international · 2020Review
- Acute and subacute oral toxicity assessment of dry encapsulated and non-encapsulated green coffee fruit extracts.Journal of food and drug analysis · 2020Article
- Dangerous mistake: an accidental caffeine overdose.BMJ case reports · 2018Article
- Nonfatal and fatal intoxications with pure caffeine - report of three different cases.Forensic science, medicine, and pathology · 2017Article
- Effects of contaminants of emerging concern on Megaselia scalaris (Lowe, Diptera: Phoridae) and its microbial community.Scientific reports · 2017Article
- Suicide by ingestion of caffeine.Egyptian journal of forensic sciences · 2017Article
- Caffeine toxicity in forensic practice: possible effects and under-appreciated sources.Forensic science, medicine, and pathology · 2016Review
- Propofol suppresses ventricular arrhythmias: a case report of acute caffeine intoxication.Acute medicine & surgeryArticle
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Caffeine (1,3,7-trimethylxanthine) is a popular mild central nervous system stimulant found in the leaves, seeds and fruits of various plants and in foodstuffs such as coffee, tea, and chocolate, among others. Caffeine is widely used and is not associated with severe side effects when consumed at relatively low doses. Although rarely observed, overdoses can occur. However, only a few fatal caffeine intoxication cases have been reported in the literature. Herein, we report the pathological examination results and information on caffeine concentrations in the blood, urine and main organs in a fatal caffeine intoxication case. Even though high caffeine concentrations were found in the systemic organs, no caffeine-related pathological changes were detected.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.