ArticleCanadian journal of surgery. Journal canadien de chirurgie2015
Prognostic value of lymph node ratio in survival of patients with locally advanced rectal cancer.
Article in Canadian journal of surgery. Journal canadien de chirurgie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic role of the lymph node ratio in node positive colorectal cancer: a meta-analysis.Oncotarget · 2016Pooled it
- Diagnostic performance of Node Reporting and Data System (Node-RADS) for assessing mesorectal lymph node in rectal cancer by CT.BMC cancer · 2024Article
- A prognostic nomogram for stage II/III rectal cancer patients treated with neoadjuvant chemoradiotherapy followed by surgical resection.BMC surgery · 2022Article
- Prognostic Factors of Recurrence and Survival in Operated Patients with Colorectal Cancer.Middle East journal of digestive diseases · 2022Article
- Article
- Lymph Node Ratio: Is It an Independent Prognostic Factor for Stage III Cutaneous Melanoma?Asian Pacific journal of cancer prevention : APJCP · 2018Article
- Comparison of Different Lymph Node Staging Systems in Patients With Resectable Colorectal Cancer.Frontiers in oncology · 2018Article
- Analysis on survival and prognostic factors in patients with resectable pancreatic adenocarcinoma.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2017Article
- The importance of a multidisciplinary team in rectal cancer management.Clujul medical (1957) · 2017Article
- Preoperative SCC Antigen, CRP Serum Levels, and Lymph Node Density in Oral Squamous Cell Carcinoma.Medicine · 2016Article
- Observational
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5 authors.
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Abstract
backgroundThe lymph node ratio (LNR) has been shown to be an important prognostic factor in patients with gastric, breast, pancreatic and colorectal cancer. We investigated the prognostic impact of the LNR in addition to TNM classification in patients with locally advanced rectal cancer.
methodsWe retrospectively analyzed patients who underwent curative resection for locally advanced rectal cancer between July 2005 and December 2010. We determined the LNR cutoff value using a receiver operating characteristic curve. The Kaplan-Meier method was used to estimate survival curves, while Cox regression analyses were used to evaluate the relationship between LNR and survival.
resultsWe included 180 patients aged 28-83 years with median follow-up of 41.8 months. The median number of lymph nodes examined and lymph nodes involved were 11.5 and 4, respectively, and the median LNR was 0.366. An LNR of 0.19 (19%) was the cutoff point to separate patients with regard to median overall survival. Median overall survival was 64.2 months for patients with an LNR of 0, 59.1 for an LNR of 0.19 or less and 37.6 for an LNR greater than 0.19 (p = 0.004). The median disease-free survival was 32.9 months for patients with an LNR of 0, 30.4 for an LNR of 0.19 or less and 17.8 for an LNR greater than 0.19 (p = 0.002).
conclusionOur results suggest that LNR should be considered an additional prognostic factor in patients with locally advanced rectal cancer.
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