ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2015
Association of Fragmented QRS with Subclinical Left Ventricular Dysfunction in Patients with Obstructive Sleep Apnea.
Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 13 citations in OpenAlex.
- Analysis of QRS complex morphology in children and adolescents with obstructive sleep apnea syndrome.European journal of pediatrics · 2024Article
- Relationship between presystolic wave and subclinical left ventricular dysfunction as assessed by myocardial performance index in patients with metabolic syndrome.The international journal of cardiovascular imaging · 2023Article
- Electrocardiographic alterations in patients with chronic obstructive pulmonary disease.World journal of cardiology · 2022Article
- Presystolic Wave is Associated with Subclinical Left Ventricular Dysfunction Assessed by Myocardial Performance Index in Type 2 Diabetes Mellitus.Arquivos brasileiros de cardiologia · 2019Article
- Ventricular Arrhythmias in Patients with Obstructive Sleep Apnea.Current cardiology reviews · 2019Review
- The Influence of Sleep Apnea on 24-Hour and Nocturnal ECG and Blood Pressure Parameters in Patients with Acute Heart Failure.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019Article
- Subclinical Left Ventricular Dysfunction in Patients with Obstructive Sleep Apnea.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2016Article
- [Fragmented QRS. Relevance in clinical practice].Herzschrittmachertherapie & Elektrophysiologie · 2015Article
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7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to investigate whether fragmented QRS (fQRS) is associated with subclinical left ventricular (LV) dysfunction in patients with obstructive sleep apnea (OSA). SUBJECTS AND
methodsA total of 141 patients with OSA who had normal LV ejection fraction (LVEF) were included in the study. The fQRS was defined as the presence of an additional R wave, notching of R or S wave or the presence of fragmentation in 2 contiguous electrocardiography (ECG) leads. Subclinical LV dysfunction was defined as the presence of a tissue Doppler-derived Tei index of ≥ 0.5 in the absence of impaired LVEF (<50%) as assessed by transthoracic echocardiography.
resultsOf the 141 patients, 71 (50.4%) had subclinical LV dysfunction. Overall, the prevalence of the fQRS was 61% (86/141). Patients with fQRS had significantly higher Tei indices than those without fQRS [median 0.66, interquartile range (IQR) 0.39 vs. median 0.40, IQR 0.15, p < 0.001]. The presence of fQRS on ECG predicted subclinical LV dysfunction in univariate logistic regression analysis [odds ratio (OR) 6.69, 95% confidence interval (CI) 3.10-14.43]. The association remained significant after adjusting for all potential confounders (OR 4.59, 95% CI 1.94-10.87).
conclusionfQRS on ECG was an independent predictor of subclinical LV dysfunction in patients with OSA. This simple tool might help to identify OSA patients who could be at risk for developing overt cardiac dysfunction.
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