Evidence map›Paper›PMID 26020294›Full record

ArticlePhysiological measurement2015

Middle-aged adults exhibit altered spatial variations in Achilles tendon wave speed.

Laura Chernak Slane, Ryan DeWall, Jack Martin, Kenneth Lee, Darryl G Thelen

Open access · greenAbstract read
In one paragraph

Article in Physiological measurement, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Growth factors in the treatment of Achilles tendon injury.Frontiers in bioengineering and biotechnology · 2023
    Review
  6. Article
  7. Article
  8. Biomaterials to Mimic and Heal Connective Tissues.Advanced materials (Deerfield Beach, Fla.) · 2019
    Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Laura Chernak SlaneDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA. Department of Radiology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Ryan DeWall
Jack Martin
Kenneth Lee
Darryl G Thelen
University of Wisconsin–Madison · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Ultrasonic analysis of the effects of aging on tendon mechanicsF31AG043216 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI SLANE, LAURA A · 2012 to 2013
$55k
NCATS NIH HHS 9U54TR000021NCATS NIH HHS UL1 TR000427NCRR NIH HHS 1UL1RR025011NCRR NIH HHS UL1 RR025011NIA NIH HHS F31 AG043216NIA NIH HHS F31AG043216
6 · The paper itself

Abstract

The purpose of this study was to investigate spatial variations in measured wave speed in the relaxed and stretched Achilles tendons of young and middle-aged adults. Wave speed was measured from the distal Achilles tendon, soleus aponeurosis, medial gastrocnemius aponeurosis and medial gastrocnemius muscle in healthy young (n = 15, aged 25   ±   4 years) and middle-aged (n = 10, aged 49   ±   4 years) adults in resting, dorsiflexed and plantarflexed postures. In both age groups, Achilles tendon wave speed decreased proximally, with the lowest wave speed measured in the gastrocnemius aponeurosis. Measured wave speed increased with passive dorsiflexion, reflecting the strain-stiffening behavior of tendons. There were no significant aging effects on wave speed in the free tendon or soleus aponeurosis. However, a significant, inverse relationship between gastrocnemius aponeurosis wave speed and age was observed in the dorsiflexed posture. We also observed significantly lower wave speeds in the gastrocnemius muscles of middle-aged adults when compared with young adults. These results suggest that Achilles tendon compliance increases in a distal-to-proximal pattern, with middle-aged adults exhibiting greater compliance in the distal gastrocnemius muscle and tendinous structures. An age-related change in the spatial variation in Achilles tendon compliance could affect localized tissue deformation patterns and injury potential within the triceps surae muscle-tendon units.

Indexed as

Achilles TendonAdultAgingFemaleHumansMaleMiddle AgedMuscle, SkeletalPostureRestSignal Processing, Computer-AssistedUltrasonography

Identifiers

PMID26020294
PMCPMC4835547
OpenAlexW1895210946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.