Trial reportPloS one2015
Suppression of Abdominal Motor Activity during Swallowing in Cats and Humans.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Evidence for peripheral and central actions of codeine to dysregulate swallowing in the anesthetized cat.Frontiers in neurology · 2024Article
- Impact of volume and rate of milk delivery on coordination of respiration and swallowing in infant pigs.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2023Article
- Review
- Deglutition and the Regulation of the Swallow Motor Pattern.Physiology (Bethesda, Md.) · 2023 · on this mapReview
- Laryngeal and swallow dysregulation following acute cervical spinal cord injury.Journal of neurophysiology · 2022Article
- Swallow Motor Pattern Is Modulated by Fixed or Stochastic Alterations in Afferent Feedback.Frontiers in human neuroscience · 2020Article
- Swallow-breathing coordination during incremental ascent to altitude.Respiratory physiology & neurobiology · 2019Article
- The Role of the Cerebellum in Control of Swallow: Evidence of Inspiratory Activity During Swallow.Lung · 2019Article
- Strategies for the Integration of Cough and Swallow to Maintain Airway Protection in Humans.Lung · 2018Article
- Neurons in the dorsomedial medulla contribute to swallow pattern generation: Evidence of inspiratory activity during swallow.PloS one · 2018Article
- Correction: Suppression of Abdominal Motor Activity during Swallowing in Cats and Humans.PloS one · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
Abstract
Diseases affecting pulmonary mechanics often result in changes to the coordination of swallow and breathing. We hypothesize that during times of increased intrathoracic pressure, swallow suppresses ongoing expiratory drive to ensure bolus transport through the esophagus. To this end, we sought to determine the effects of swallow on abdominal electromyographic (EMG) activity during expiratory threshold loading in anesthetized cats and in awake-healthy adult humans. Expiratory threshold loads were applied to recruit abdominal motor activity during breathing, and swallow was triggered by infusion of water into the mouth. In both anesthetized cats and humans, expiratory cycles which contained swallows had a significant reduction in abdominal EMG activity, and a greater percentage of swallows were produced during inspiration and/or respiratory phase transitions. These results suggest that: a) spinal expiratory motor pathways play an important role in the execution of swallow, and b) a more complex mechanical relationship exists between breathing and swallow than has previously been envisioned.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.