ReviewIranian journal of pediatrics2014
Congenital hypothyroidism screening program in iran; a systematic review and metaanalysis.
Review in Iranian journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Increasing prevalence of congenital hypothyroidism emerges as a growing concern in Jordan.World journal of clinical pediatrics · 2025Article
- Translational medicine: An effective approach to improve healthcare by research and innovation in developing countries.Medicine · 2025Review
- Congenital hypothyroidism in India: A systematic review and meta-analysis of prevalence, screen positivity rates, and etiology.The Lancet regional health. Southeast Asia · 2022Article
- Prevalence of transient congenital hypothyroidism among neonates.Annals of medicine and surgery (2012) · 2021Article
- Risk factors for transient and permanent congenital hypothyroidism: a population-based case-control study.Thyroid research · 2021Article
- Implementing the six sigma model on the treatment of congenital hypothyroidism: An analytical hierarchy process.Medical journal of the Islamic Republic of Iran · 2021Article
- Assessment of intelligence quotient score in children at the age of six with suspected congenital hypothyroidism: A retrospective cohort study.Medical journal of the Islamic Republic of Iran · 2020Article
- Higher prevalence of permanent congenital hypothyroidism in the Southwest of Iran mostly caused by dyshormonogenesis: a five-year follow-up study.Archives of endocrinology and metabolism · 2018Article
- Article
- Worldwide Recall Rate in Newborn Screening Programs for Congenital Hypothyroidism.International journal of endocrinology and metabolism · 2017Review
- Permanent and Transient Congenital Hypothyroidism in Hamadan West Province of Iran.International journal of endocrinology and metabolism · 2016Article
- Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases.Iranian Red Crescent medical journal · 2015Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveUnrecognized congenital hypothyroidism (CH) leads to mental retardation. Newborn screening and thyroid therapy started within 2 weeks of age can normalize cognitive development. In this systematic review, the local results of the national CH screening program in different provinces in Iran are reviewed and evaluated.
methodsLiterature on the CH screening, the national databases including SID, Medlib, Iran Medex, Magiran as well as international databases including PubMed/Medline, ISI Web of Knowledge and web of science, EMBASE, SCOPUS and Google Scholar. Appraisal was guided by a checklist assessing clarity of aims and research questions. The 95% confidence intervals were calculated by I-square models. Meta regression was introduced to explore the heterogeneity between studies.
findingsWe identified 25 samples including 1425124 neonates in our country. Data were Meta analyzed using random-effects models, and we found a TSH levels of 19633 babies in the first sampling were greater than the cut-off level (TSH ≥5mIU/L). The pooled recall rate was 0.014 (95 % CI: 0.013 - 0.015). According to Meta analysis the overall incidence of CH was 2/1000 (95% CI: .002 - .002). The incidence of CH did not appear to be increasing over time (P=0.08).
conclusionConsidering TSH ≥5mIU/L as a cut-off point for recalling neonates and low positive predictive value (14%) of this point shows that more investigation and research is needed for establishing accurate level of TSH as a criterion for recalling patients.
Indexed as
Identifiers
26019769PMC4442825W2099807683What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.