Evidence map›Paper›PMID 26019630›Full record

ArticleBiotechnology, biotechnological equipment2015

Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging

Rumiana Bakalova, Desislava Lazarova, Biliana Nikolova, Severina Atanasova, Genoveva Zlateva, Zhivko Zhelev, Ichio Aoki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology, biotechnological equipment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rumiana BakalovaDiagnostic Imaging Program, Molecular Imaging Center, National Institute of Radiological Sciences, Anagawa , Chiba , Japan ; Department of Physics, Biophysics and Roentgenology, Faculty of Medicine, Sofia University "St Kliment Ohridski" , Sofia , Bulgaria.
Desislava LazarovaDepartment of Physics, Biophysics and Roentgenology, Faculty of Medicine, Sofia University "St Kliment Ohridski" , Sofia , Bulgaria.
Biliana NikolovaDepartment of Electroinduced and Adhesive Properties, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences , Sofia , Bulgaria.
Severina AtanasovaDepartment of Electroinduced and Adhesive Properties, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences , Sofia , Bulgaria.
Genoveva ZlatevaDepartment of Physics, Biophysics and Roentgenology, Faculty of Medicine, Sofia University "St Kliment Ohridski" , Sofia , Bulgaria.
Zhivko ZhelevDiagnostic Imaging Program, Molecular Imaging Center, National Institute of Radiological Sciences, Anagawa , Chiba , Japan ; Department of Electroinduced and Adhesive Properties, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences , Sofia , Bulgaria ; Department of Medicinal Chemistry and Biochemistry, Faculty of Medicine, Trakia University , Stara Zagora , Bulgaria.
Ichio AokiDiagnostic Imaging Program, Molecular Imaging Center, National Institute of Radiological Sciences, Anagawa , Chiba , Japan.
Bulgarian Academy of Sciences · BGSofia University "St. Kliment Ohridski" · BGImaging Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was designed to investigate whether poly-ion complex hollow vesicles (polymersomes), based on chemically modified chitosan, are appropriate for passive tumour targeting in the context of their application as drug carriers. The experiments were performed on colon cancer-grafted mice. The mice were subjected to anaesthesia and injected intravenously with water-soluble nanoparticles: (1) QD

Indexed as

cancerdrug-delivery systemsfluorescent imagingnanoparticlespolymersomesquantum dot

Identifiers

PMID26019630
PMCPMC4434099
OpenAlexW2053204709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.