Evidence map›Paper›PMID 26019537›Full record

ArticleBiotechnology, biotechnological equipment2014

VEGF expression, microvessel density and dendritic cell decrease in thyroid cancer.

Maya Gulubova, Koni Ivanova, Julian Ananiev, Julieta Gerenova, Aleksandar Zdraveski, Hristo Stoyanov, Tatyana Vlaykova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology, biotechnological equipment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maya GulubovaDepartment of General and Clinical Pathology, Medical Faculty, Trakia University , Stara Zagora , Bulgaria.
Koni IvanovaDepartment of General and Clinical Pathology, Medical Faculty, Trakia University , Stara Zagora , Bulgaria.
Julian AnanievDepartment of General and Clinical Pathology, Medical Faculty, Trakia University , Stara Zagora , Bulgaria.
Julieta GerenovaDepartment of Endocrinology, Medical Faculty, Trakia University , Stara Zagora , Bulgaria.
Aleksandar ZdraveskiDepartment of General Surgery, Medical Faculty, Trakia University , Stara Zagora , Bulgaria.
Hristo StoyanovDepartment of General Surgery, Medical Faculty, Trakia University , Stara Zagora , Bulgaria.
Tatyana VlaykovaDepartment of Chemistry and Biochemistry, Medical Faculty, Trakia University , Stara Zagora , Bulgaria.
Trakia University · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer is one of the five most common cancers in the age between 20 and 50 years. Many factors including the potent angiogenic vascular endothelial growth factor (VEGF) and different dendritic cell types are known to be related to thyroid tumourogenesis. The study was performed to address the expression of VEGF and microvessel density in thyroid cancers and to evaluate the effect of VEGF expression in thyroid tumour cells on the dendritic cells. We investigated 65 patients with different types of thyroid carcinomas: papillary (PTC), oncocytic (OTC), follicular (FTC) and anaplastic (ATC), immunohistochemically with antibodies against VEGF, CD1a, CD83, S100 and CD31. Our results suggest that the expression of VEGF is significantly more often in PTC than ATC (92.3% vs. 60.0%,

Indexed as

CD31dendritic cellmicrovessel densityprognosisthyroid cancerVEGF

Identifiers

PMID26019537
PMCPMC4433839
OpenAlexW2028128829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.