Evidence map›Paper›PMID 26019522›Full record

ArticleBiotechnology, biotechnological equipment2014

Economic consequences of the vaccination against hepatitis A in the Bulgarian healthcare setting.

Maria Dimitrova, Guenka Petrova, Konstantin Tachkov, Maria Krasteva Bozhkova, Maria Kamusheva, Konstantin Mitov

Open access · goldAbstract read
In one paragraph

Article in Biotechnology, biotechnological equipment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria DimitrovaOrganization and Economy of Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
Guenka PetrovaOrganization and Economy of Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
Konstantin TachkovOrganization and Economy of Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
Maria Krasteva BozhkovaMedicine College, Medical University of Plovdiv , Plovdiv , Bulgaria.
Maria KamushevaOrganization and Economy of Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
Konstantin MitovOrganization and Economy of Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
Medical University of Sofia · BGMedical University Plovdiv · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the present analysis is to calculate and compare the costs and results of the implication of the inactivated vaccine against hepatitis A virus (HAV) in the Bulgarian healthcare setting in the period of 2002-2012. A combined pharmacoeconomic and epidemiological study was performed on the basis of the prevalence of hepatitis A infection in this 10-year period. The investments in the vaccination were considered as costs and the avoided costs in the case of vaccination of all one-year old children in the population - as benefits. The results show that the vaccination of one-year-old children would be cost effective to the healthcare system in the years with an epidemiologic outbreak, as in these years the total cost of treatment of patients with hepatitis A infection exceeds the cost for vaccination of the whole one-year-old cohort. The critical threshold is 4600 infected patients per year that equalize the benefits to costs. The inclusion of HAV vaccine in the National Immunization Calendar would be cost effective for the healthcare system when the vaccination is performed in certain risk groups and could help to decrease the circulation of the virus in the general population.

Indexed as

cost–benefit analysiscost of vaccinationHAV vaccineprevalence

Identifiers

PMID26019522
PMCPMC4433896
OpenAlexW1990782181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.