Evidence map›Paper›PMID 26019504›Full record

ArticleBiotechnology, biotechnological equipment2014

Current state of the opportunities for derivation of germ-like cells from pluripotent stem cells: are you a man, or a mouse?

Rumena Petkova, Borislav Arabadjiev, Stoyan Chakarov, Roumen Pankov

Open access · goldAbstract read
In one paragraph

Article in Biotechnology, biotechnological equipment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rumena PetkovaScientific Technological Service (STS) Ltd. , Sofia , Bulgaria.
Borislav ArabadjievScientific Technological Service (STS) Ltd. , Sofia , Bulgaria ; Department of Cell Biology, Histology and Embryology, and Department of Biochemistry, Faculty of Biology, Sofia University 'St. Kliment Ohridsky' , Sofia , Bulgaria.
Stoyan ChakarovDepartment of Cell Biology, Histology and Embryology, and Department of Biochemistry, Faculty of Biology, Sofia University 'St. Kliment Ohridsky' , Sofia , Bulgaria.
Roumen PankovDepartment of Cell Biology, Histology and Embryology, and Department of Biochemistry, Faculty of Biology, Sofia University 'St. Kliment Ohridsky' , Sofia , Bulgaria.
Sofia University "St. Kliment Ohridski" · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concept of pluripotency as a prerogative of cells of early mammal embryos and cultured embryonic stem cells (ESC) has been invalidated with the advent of induced pluripotent stem cells. Later, it became clear that the ability to generate all cell types of the adult organism is also a questionable aspect of pluripotency, as there are cell types, such as germ cells, which are difficult to produce from pluripotent stem cells. Recently it has been proposed that there are at least two different states of pluripotency; namely, the naïve, or ground state, and the primed state, which may differ radically in terms of timeline of existence, signalling mechanisms, cell properties, capacity for differentiation into different cell types, etc. Germ-like male and female rodent cells have been successfully produced

Indexed as

germ cellsground statehESCmESCPGCpluripotency

Identifiers

PMID26019504
PMCPMC4434091
OpenAlexW2002237993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.