ArticlePhysiological reports2015
Sympathetic vasomotor outflow and blood pressure increase during exercise with expiratory resistance.
Article in Physiological reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Inspiratory Muscle Training in Intermittent Sports Modalities: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Current limits for flowmeter resistance in metabolic carts can negatively affect exercise performance.Physiological reports · 2021Trial
- Effects of resistance exercise intensity on cerebral blood flow and cerebrovascular reactivity in healthy young males: A pilot study.Physiological reports · 2025Article
- I-EPAP Device in COPD With Dynamic Hyperinflation: Effects on Maximal Exercise Tolerance and Physiological Adjustments.Respiratory care · 2023Article
- Sex differences in blood pressure and inactive limb blood flow responses during dynamic leg exercise with increased inspiratory muscle work.Nagoya journal of medical science · 2022Article
- Effects of Oral Leak Size on Valsalva Responses.Journal of community hospital internal medicine perspectives · 2022Article
- Combined influence of inspiratory loading and locomotor subsystolic cuff inflation on cardiovascular responses during submaximal exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- No Evidence That Hyperpnea-Based Respiratory Muscle Training Affects Indexes of Cardiovascular Health in Young Healthy Adults.Frontiers in physiology · 2020Article
- Muscle sympathetic nerve activity during exercise.The journal of physiological sciences : JPS · 2019Review
- Competition for blood flow distribution between respiratory and locomotor muscles: implications for muscle fatigue.Journal of applied physiology (Bethesda, Md. : 1985) · 2018Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of the present study was to elucidate the effect of increasing expiratory muscle work on sympathetic vasoconstrictor outflow and arterial blood pressure (BP) during dynamic exercise. We hypothesized that expiratory muscle fatigue would elicit increases in sympathetic vasomotor outflow and BP during submaximal exercise. The subjects performed four submaximal exercise tests; two were maximal expiratory pressure (PE max) tests and two were muscle sympathetic nerve activity (MSNA) tests. In each test, the subjects performed two 10-min exercises at 40% peak oxygen uptake using a cycle ergometer in a semirecumbent position [spontaneous breathing for 5 min and voluntary hyperpnoea with and without expiratory resistive breathing for 5 min (breathing frequency: 60 breaths/min, inspiratory and expiratory times were set at 0.5 sec)]. PE max was estimated before and immediately after exercises. MSNA was recorded via microneurography of the right median nerve at the elbow. PE max decreased following exercise with expiratory resistive breathing, while no change was found without resistance. A progressive increase in MSNA burst frequency (BF) appeared during exercise with expiratory resistance (MSNA BF, without resistance: +22 ± 5%, with resistance: +44 ± 8%, P < 0.05), accompanied by an augmentation of BP (mean BP, without resistance: +5 ± 2%, with resistance: +29 ± 5%, P < 0.05). These results suggest that an enhancement of expiratory muscle activity leads to increases in sympathetic vasomotor outflow and BP during dynamic leg exercise.
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