Evidence map›Paper›PMID 26019232›Full record

Trial reportSexually transmitted infections2015

Developing and testing accelerated partner therapy for partner notification for people with genital Chlamydia trachomatis diagnosed in primary care: a pilot randomised controlled trial.

Claudia S Estcourt, Lorna J Sutcliffe, Andrew Copas, Catherine H Mercer, Tracy E Roberts, Louise J Jackson, Merle Symonds, Laura Tickle, Pamela Muniina, Greta Rait and 4 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Sexually transmitted infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Claudia S EstcourtBlizard Institute, Barts and the London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Lorna J SutcliffeBlizard Institute, Barts and the London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Andrew CopasResearch Department of Infection & Population Health, University College London, London, UK.
Catherine H MercerResearch Department of Infection & Population Health, University College London, London, UK.
Tracy E RobertsHealth Economics Unit, School of Population and Health Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Louise J JacksonHealth Economics Unit, School of Population and Health Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Merle SymondsBlizard Institute, Barts and the London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Laura TickleBarts Sexual Health Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
Pamela MuniinaResearch Department of Infection & Population Health, University College London, London, UK.
Greta RaitResearch Department of Infection & Population Health, University College London, London, UK.
Anne M JohnsonResearch Department of Infection & Population Health, University College London, London, UK.
Kazeem AderogbaDepartment of Sexual Health, Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
Sarah CreightonHomerton Sexual Health Services, Homerton Hospital, London, UK.
Jackie A CassellDivision of Primary Care & Public Health, Brighton & Sussex Medical School, University of Brighton, Brighton, UK.
University College London · GBQueen Mary University of London · GBUniversity of Birmingham · GBBrighton and Sussex Medical School · GBEastbourne District General Hospital · GBHomerton University Hospital · GBSt Bartholomew's Hospital · GB

Funding

Department of Health RP-PG-0707-10208Medical Research Council MR/K010174/1
6 · The paper itself

Abstract

backgroundAccelerated partner therapy (APT) is a promising partner notification (PN) intervention in specialist sexual health clinic attenders. To address its applicability in primary care, we undertook a pilot randomised controlled trial (RCT) of two APT models in community settings.

methodsThree-arm pilot RCT of two adjunct APT interventions: APTHotline (telephone assessment of partner(s) plus standard PN) and APTPharmacy (community pharmacist assessment of partner(s) plus routine PN), versus standard PN alone (patient referral). Index patients were women diagnosed with genital chlamydia in 12 general practices and three community contraception and sexual health (CASH) services in London and south coast of England, randomised between 1 September 2011 and 31 July 2013.

results199 women described 339 male partners, of whom 313 were reported by the index as contactable. The proportions of contactable partners considered treated within 6 weeks of index diagnosis were APTHotline 39/111 (35%), APTPharmacy 46/100 (46%), standard patient referral 46/102 (45%). Among treated partners, 8/39 (21%) in APTHotline arm were treated via hotline and 14/46 (30%) in APTPharmacy arm were treated via pharmacy.

conclusionsThe two novel primary care APT models were acceptable, feasible, compliant with regulations and capable of achieving acceptable outcomes within a pilot RCT but intervention uptake was low. Although addition of these interventions to standard PN did not result in a difference between arms, overall PN uptake was higher than previously reported in similar settings, probably as a result of introducing a formal evaluation. Recruitment to an individually randomised trial proved challenging and full evaluation will likely require service-level randomisation. TRIAL REGISTRATION NUMBER: Registered UK Clinical Research Network Study Portfolio id number 10123.

Indexed as

Primary Health CareSexual PartnersAdultAmbulatory CareChlamydia InfectionsChlamydia trachomatisContact TracingFeasibility StudiesHumansMalePatient Acceptance of Health CarePilot ProjectsProgram DevelopmentReferral and ConsultationSexual BehaviorCHLAMYDIA TRACHOMATISCLINICAL STI CARECOMPEX INTERVENTIONSPARTNER NOTIFICATIONPRIMARY CARE

Identifiers

PMID26019232
PMCPMC4680194
OpenAlexW2210613830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.